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颈椎手术后的神经移植:多机构病例系列及文献综述

Nerve Transfers After Cervical Spine Surgery: Multi-Institutional Case Series and Review of the Literature.

作者信息

Lubelski Daniel, Pennington Zach, Kopparapu Srujan, Sciubba Daniel M, Bishop Allen T, Shin Alexander Y, Spinner Robert J, Belzberg Allan J

机构信息

Department of Neurosurgery, Johns Hopkins University, Baltimore, Maryland, USA.

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

出版信息

World Neurosurg. 2021 Dec;156:e222-e228. doi: 10.1016/j.wneu.2021.09.039. Epub 2021 Sep 15.

Abstract

BACKGROUND

Up to 10% of cervical spine surgeries are complicated by postoperative weakness. Although many patients recover with nonoperative management, some require surgery for restoration of function.

OBJECTIVE

To present the indications and outcomes of patients undergoing nerve transfers after developing weakness secondary to cervical spine decompression.

METHODS

A retrospective review of patients from 2 academic medical centers who underwent nerve transfer for C5-6 root injury after cervical spine surgery was performed.

RESULTS

Of the 10 treated patients, 9 experienced recovery at last follow-up, demonstrating improvements in strength and motion in the affected muscles. Successful nerve transfers occurred between 3 and 8 months after the index spinal surgery and included spinal accessory nerve to suprascapular nerve, triceps branch to anterior division of the axillary nerve, and/or ulnar or median fascicles to motor branches of the musculocutaneous nerve. The unsuccessful patient underwent nerve transfer surgery approximately 11 months after the index operation and failed to obtain functional recovery.

CONCLUSIONS

Patients who experience C5-6 weakness after cervical spine surgery should be evaluated and considered for nerve transfer surgery if they have continued severe functional deficits at 6 months postoperatively. Earlier referral for nerve transfer is associated with improved functional outcomes in this cohort.

摘要

背景

高达10%的颈椎手术会并发术后肌无力。尽管许多患者通过非手术治疗得以康复,但仍有一些患者需要手术来恢复功能。

目的

介绍颈椎减压术后出现肌无力的患者接受神经移植的适应证及疗效。

方法

对来自2个学术医疗中心的患者进行回顾性研究,这些患者在颈椎手术后因C5-6神经根损伤接受了神经移植。

结果

在10例接受治疗的患者中,9例在末次随访时恢复,受累肌肉的力量和活动度均有改善。成功的神经移植发生在初次脊柱手术后3至8个月,包括副神经至肩胛上神经、肱三头肌分支至腋神经前支,和/或尺侧或正中神经束至肌皮神经运动支。未成功的患者在初次手术后约11个月接受了神经移植手术,但未能获得功能恢复。

结论

颈椎手术后出现C5-6肌无力的患者,如果术后6个月仍有持续严重的功能缺损,应接受评估并考虑进行神经移植手术。在此队列中,更早转诊进行神经移植与更好的功能结局相关。

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