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腹腔镜经腹会阴联合切除术治疗老年局部晚期肛管直肠恶性黑色素瘤:一例报告

Locally advanced anorectal malignant melanoma in septuagenarian patient treated by laparoscopic abdominoperineal resection: A case report.

作者信息

Futori Takuya, Enomoto Tsuyoshi, Owada Yohei, Ohara Yusuke, Matsumura Hideki, Oda Tatsuya

机构信息

University of Tsukuba, Faculty of Medicine, Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, 1-1-1 Tennnodai, Tsukuba-shi, Ibaraki-ken 305-8575, Japan.

出版信息

Int J Surg Case Rep. 2021 Oct;87:106378. doi: 10.1016/j.ijscr.2021.106378. Epub 2021 Sep 6.

Abstract

INTRODUCTION

Anorectal malignant melanoma (ARMM) is a rare disease with a poor prognosis. In cases involving locally advanced disease, the treatment strategy is difficult, especially in octogenarian patients, because the prognosis is poor, despite the corresponding decrease or loss of the anal function.

PRESENTATION OF CASE

A 78-year-old woman was admitted to a local hospital with chief complaints of severe anal discomfort due to an egg-sized tumor that was protruding out of the anus and melena. A diagnosis of ARMM was confirmed based on the examination of biopsy specimens and imaging study showed swollen lymph nodes on the dorsal side of the middle rectum and left internal iliac lymph nodes. Laparoscopic abdominoperineal resection with left lateral lymph node dissection was performed. The examination of the resected specimen revealed two polypoid tumors with a maximum diameter of 38 mm and 14 mm with a metastatic lymph node of 62 mm in the mesorectum. The postoperative course was uneventful. Relapse and local recurrence free survival without any complaints was obtained for more than 12 months.

DISCUSSION

With respect to locoregional disease control, it has been reported that abdominoperineal resection can obtain better control of local disease in comparison to local resection. Laparoscopic surgery is advantageous in its facilitation of an early postoperative recovery for elderly patient.

CONCLUSION

Laparoscopic abdominoperineal resection may control locoregional disease and improve the patient's QOL with early postoperative recovery. -even in septuagenarian patients-may become a treatment strategy for advanced ARMM.

摘要

引言

肛管恶性黑色素瘤(ARMM)是一种预后较差的罕见疾病。对于局部晚期疾病的病例,治疗策略具有挑战性,尤其是对于八旬患者,因为尽管肛门功能相应下降或丧失,但预后仍然很差。

病例介绍

一名78岁女性因肛门处有鸡蛋大小的肿瘤突出并伴有黑便导致严重肛门不适为主诉入住当地医院。根据活检标本检查确诊为ARMM,影像学检查显示直肠中背侧和左髂内淋巴结肿大。行腹腔镜腹会阴联合切除术并清扫左侧淋巴结。切除标本检查发现两个息肉样肿瘤,最大直径分别为38mm和14mm,直肠系膜中有一个62mm的转移淋巴结。术后过程顺利。获得了超过12个月的无复发和局部无复发生存期,且无任何不适。

讨论

关于局部区域疾病控制,据报道与局部切除相比,腹会阴联合切除术能更好地控制局部疾病。腹腔镜手术有利于老年患者术后早期恢复。

结论

腹腔镜腹会阴联合切除术可能控制局部区域疾病,并通过术后早期恢复改善患者生活质量。即使对于七十多岁的患者,也可能成为晚期ARMM的一种治疗策略。

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