Department of Medical Imaging, John Hunter Hospital, Locked Bag 1, Newcastle Region Mail Center, Newcastle, NSW 2310, Australia; Newcastle University Faculty of Health, Callaghan Campus, Newcastle, NSW, Australia.
Newcastle University Faculty of Health, Callaghan Campus, Newcastle, NSW, Australia; Department of Neurology, John Hunter Hospital, Newcastle, Australia; Hunter Medical Research Institute, Newcastle, Australia.
Mult Scler Relat Disord. 2021 Nov;56:103262. doi: 10.1016/j.msard.2021.103262. Epub 2021 Sep 13.
The theory that multiple sclerosis is related to venous pressure has been discredited due to previous operator dependent diagnostic criteria and premature attempts at treatment. (1) An elevation in venous pressure may only be a component of the compliance changes found in MS. (2) The neck veins may only supply a component of the venous pressure elevation found intracranially. Although a more targeted approach towards neck angioplasty (both towards disease subtype and those with more favorable stenoses) may be beneficial, we would advocate caution. We encourage others to give the venous pressure theory a second chance and to replicate our work.
由于先前依赖操作者的诊断标准和过早尝试治疗，多发性硬化症与静脉压力有关的理论已被否定。（1）静脉压力升高可能只是 MS 中发现的顺应性变化的一个组成部分。（2）颈静脉可能仅提供颅内发现的静脉压力升高的一部分。虽然针对颈动脉成形术（针对疾病亚型和那些狭窄程度更有利的患者）的更有针对性的方法可能是有益的，但我们建议谨慎行事。我们鼓励其他人再次尝试静脉压力理论，并复制我们的工作。
