McClelland S J, Rudolf L M
Columbia University College of Physicians and Surgeons, New York, New York.
Orthop Rev. 1986 Apr;15(4):223-7.
Clinically significant myositis ossificans of the distal thigh following virginal porous-ingrowth total knee arthroplasty has not been previously reported. Associated and potentially contributing factors in this particular case were (1) the patient's preoperative hypertrophic gonarthrosis, (2) our difficulty in regulating her postoperative sodium warfarin (Coumadin) dosages, (3) the postoperative knee manipulation, and (4) possibly, the additional surgical exposure of this patient's distal femur required to use the femur-based alignment instrumentation. Postoperative heterotopic ossification developing in the vicinity of a porous-ingrowth total knee prosthesis can have clinical significance. Treatment of this problem by a means that does not interfere with early bone ingrowth into the implant is a practical concern that warrants investigation.
首次报道了初次行微孔长入型全膝关节置换术后大腿远端发生具有临床意义的骨化性肌炎。该特殊病例中相关的潜在促成因素包括：（1）患者术前膝关节肥大性骨关节炎；（2）我们在调节其术后华法林钠（香豆素）剂量时遇到困难；（3）术后膝关节手法操作；（4）可能是为了使用基于股骨的对线器械而对该患者股骨远端进行的额外手术显露。在微孔长入型全膝关节假体附近发生的术后异位骨化可能具有临床意义。采用不干扰早期骨长入植入物的方法来治疗这一问题是一个值得研究的实际问题。
