Yuan Bingjian, Wang Huanzhong
Department of Plant Science and Landscape Architecture, University of Connecticut, Storrs, CT, United States.
Institute for System Genomics, University of Connecticut, Storrs, CT, United States.
Front Plant Sci. 2021 Sep 3;12:719606. doi: 10.3389/fpls.2021.719606. eCollection 2021.
Plant small peptides, including CLAVATA3/EMBRYO SURROUNDING REGION-RELATED (CLE) and Epidermal Patterning Factor-Like (EPFL) peptides, play pivotal roles in coordinating developmental processes through cell-cell communication. Recent studies have revealed that the phloem-derived CLE peptides, CLE41/44 and CLE42, promote (pro-)cambial cell proliferation and inhibit xylem cell differentiation. The endodermis-derived EPFL peptides, EPFL4 and EPFL6, modulate vascular development in the stem. Further, several other peptide ligands CLE9, CLE10, and CLE45 play crucial roles in regulating vascular development in the root. The peptide signaling pathways interact with each other and crosstalk with plant hormone signals. In this mini-review, we summtarize the recent advances on peptides function in vascular development and discuss future perspectives for the research of the CLE and EPFL peptides.
植物小肽，包括CLAVATA3/胚胎周围区域相关（CLE）肽和类表皮模式因子（EPFL）肽，通过细胞间通讯在协调发育过程中发挥关键作用。最近的研究表明，韧皮部来源的CLE肽CLE41/44和CLE42促进形成层细胞增殖并抑制木质部细胞分化。内皮层来源的EPFL肽EPFL4和EPFL6调节茎中的维管发育。此外，其他几种肽配体CLE9、CLE10和CLE45在调节根中的维管发育中起关键作用。肽信号通路相互作用并与植物激素信号相互作用。在本综述中，我们总结了肽在维管发育中功能的最新进展，并讨论了CLE和EPFL肽研究的未来前景。
