众多肿瘤与一个内分泌部位的故事：垂体转移瘤病例系列
A tale of many tumors and one endocrine site: A case series of pituitary metastases.
作者信息
Dabbous Zeinab, Mohamed Muna, Benjamin Silas, Green Fiona, Salman Hassoun, Elhadd Tarik
机构信息
Endocrine Department, Hamad Medical Corporation, Doha, Qatar.
Department of Medicine, Dumfries and Galloway Royal Infirmary, Dumfries, Scotland E-mail:
出版信息
Qatar Med J. 2021 Sep 9;2021(2):38. doi: 10.5339/qmj.2021.38. eCollection 2021.
BACKGROUND
Metastases to the pituitary gland are extremely rare with an incidence rate reported from an autopsy series of 1.8%-12%, and only 20% was diagnosed clinically. Tumors that commonly metastasize are breast and lung tumors.
CASE SERIES
We present a series of five cases, including four female patients and one male patient with metastatic cancer. Two women had metastatic small lung cancer and presented with diabetes insipidus (DI). Two women had metastatic breast cancer, of which one presented with DI and the other with panhypopituitarism. The male patient had bronchogenic adenocarcinoma and presented with DI.
CONCLUSION
Our case series confirmed earlier reports that DI is the most common presentation of metastases to the pituitary gland.
背景
垂体转移瘤极为罕见，尸检系列报道的发生率为1.8%-12%，临床诊断率仅为20%。常见转移的肿瘤为乳腺和肺部肿瘤。
病例系列
我们报告了一系列5例病例，包括4例女性患者和1例男性转移性癌患者。2例女性患有转移性小肺癌，表现为尿崩症（DI）。2例女性患有转移性乳腺癌，其中1例表现为尿崩症，另1例表现为垂体功能减退。男性患者患有支气管源性腺癌，表现为尿崩症。
结论
我们的病例系列证实了早期报道，即尿崩症是垂体转移瘤最常见的表现。
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