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以孤立性腹膜淋巴瘤病形式出现的非霍奇金淋巴瘤:一例报告及文献综述

Non-Hodgkin's Lymphoma Presenting as Isolated Peritoneal Lymphomatosis: A Case Report and Literature Review.

作者信息

Zhu Min, Wu Zhixuan, Yang Zhaoxia, Ning Bo, Yu Shengjie, Gu Xiling, Yu Huihong

机构信息

Department of Gastroenterology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Department of Urology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

出版信息

Front Oncol. 2021 Sep 2;11:719554. doi: 10.3389/fonc.2021.719554. eCollection 2021.

Abstract

Peritoneal lymphomatosis is extremely rare and associated with poor prognosis. Most practitioners only pay more attention to peritoneal carcinomatosis. However, peritoneal lymphomatosis can be neglected and misdiagnosed. We report a teenager with 10 days of abdominal distension and pain accompanied by computed tomography scan suggesting diffuse thickening of the peritoneum and omentum and abdominopelvic effusion. Tuberculous peritonitis and peritoneal carcinomatosis were initially suspected. However, it was finally confirmed as non-Hodgkin's B-cell lymphoma by omentum biopsies. He achieved complete remission after chemotherapy and autologous stem cell transplantation. But unfortunately, he suffered a relapse and died 10 months after diagnosis. Following a review of the literature, it can be concluded that the discovery of lymphomatosis in peritoneum is a rare finding. Lymphoma should be considered in the differential diagnosis of unexplained peritoneal thickening on computed tomography, and this case emphasizes the importance of early pathological diagnosis to make sure that the right treatment can be started opportunely.

摘要

腹膜淋巴瘤极为罕见,且预后较差。大多数从业者更关注腹膜癌病。然而,腹膜淋巴瘤可能被忽视和误诊。我们报告一名青少年,有10天的腹胀和腹痛,计算机断层扫描显示腹膜和大网膜弥漫性增厚以及腹腔盆腔积液。最初怀疑为结核性腹膜炎和腹膜癌病。然而,最终通过大网膜活检确诊为非霍奇金B细胞淋巴瘤。他在化疗和自体干细胞移植后实现了完全缓解。但不幸的是,他在诊断后10个月复发并死亡。经文献复习后可以得出结论,腹膜淋巴瘤的发现是一个罕见的情况。在计算机断层扫描发现无法解释的腹膜增厚进行鉴别诊断时应考虑淋巴瘤,该病例强调了早期病理诊断以确保能及时开始正确治疗的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc77/8443791/9c5b362195ea/fonc-11-719554-g001.jpg

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