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一项关于捷克爱丁堡认知与行为肌萎缩侧索硬化症筛查(ECAS)的规范研究:简要报告。

A normative study of the Czech Edinburgh Cognitive and Behavioural ALS Screen (ECAS): a brief report.

机构信息

First Faculty of Medicine, Department of Neurology and Centre of Clinical Neuroscience, Charles University and General University Hospital, Prague, Czech Republic.

Human Cognitive Neuroscience - Department of Psychology, The University of Edinburgh, Edinburgh, UK.

出版信息

Clin Neuropsychol. 2021 Dec;35(sup1):S65-S72. doi: 10.1080/13854046.2021.1978553. Epub 2021 Sep 18.

Abstract

UNLABELLED

Edinburgh Cognitive and Behavioural ALS Screen (ECAS) is a brief, standardized assessment of cognitiveimpairment inamyotrophic lateral sclerosis.

OBJECTIVE

We aimed to createa normative dataset for the ECAS Czech version (ECAS-CZ) in order to make the assessment applicable for clinical settings.

METHOD

Included were 102 healthy participants (mean age: 54.92 ± 14.55; education: 14.52 ± 2.44; 54:48 females/males) that fulfilled rigorous exclusion criteria and controlled for depressive symptoms.

RESULTS

The internal consistency of ECAS-CZ was acceptable (Cronbach's = .69). We found medium correlations ( ≈ .5) of age and education with ECAS-CZ Total score but not with gender. Cut-offs with -2 's threshold are presented for the differentiation of cognitive impairment. We report percentile values for ECAS-CZ Total including all subscales.

CONCLUSION

We provide normative values for ECAS-CZ that are well suited for the detection of cognitive impairment in clinical settings especially for patients with ALS.Supplemental data for this article is available online at https://doi.org/10.1080/13854046.2021.1978553 .

摘要

未加标签

爱丁堡认知和行为性肌萎缩侧索硬化症筛查(ECAS)是一种对肌萎缩侧索硬化症患者认知障碍进行的简短、标准化评估。

目的

我们旨在创建 ECAS 捷克语版本(ECAS-CZ)的常模数据集,以便使评估适用于临床环境。

方法

纳入了 102 名符合严格排除标准且控制抑郁症状的健康参与者(平均年龄:54.92±14.55;教育程度:14.52±2.44;54:48 名女性/男性)。

结果

ECAS-CZ 的内部一致性可接受(Cronbach's α=.69)。我们发现年龄和教育程度与 ECAS-CZ 总分中度相关(≈.5),但与性别无关。-2 个阈值的截断值用于区分认知障碍。我们报告了包括所有子量表在内的 ECAS-CZ 总分的百分位值。

结论

我们提供了 ECAS-CZ 的常模值,非常适合在临床环境中检测认知障碍,特别是用于肌萎缩侧索硬化症患者。本文的补充数据可在 https://doi.org/10.1080/13854046.2021.1978553 上获取。

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