Whelan H T, Moore P
Department of Neurology, Vanderbilt University, Nashville, Tenn.
Pediatr Neurosci. 1987;13(3):113-7. doi: 10.1159/000120313.
Lymphomatoid granulomatosis is a vasocentric lymphoreticular proliferative disease. Some patients go on to develop frank neoplasia. Central nervous system involvement with lymphomatoid granulomatosis has been reported previously in the literature. We are presenting a childhood case evaluated with magnetic resonance imaging and x-ray computerized tomography who developed severe tissue destruction with pleomorphic cellular infiltrate and oligoclonal light chains. This report adds information regarding neuroimaging as well as immunopathology data relevant to the basic biology of this disease.
淋巴瘤样肉芽肿病是一种以血管为中心的淋巴网状增殖性疾病。一些患者会发展为明显的肿瘤形成。此前文献中已有关于淋巴瘤样肉芽肿病累及中枢神经系统的报道。我们现报告一例儿童病例，该病例接受了磁共振成像和X线计算机断层扫描评估，其出现了严重的组织破坏，并伴有多形性细胞浸润和寡克隆轻链。本报告补充了有关神经影像学以及与该疾病基础生物学相关的免疫病理学数据的信息。
