Department of Urology, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.
Department of Mathematics, Technical University of Munich, Boltzmannstr. 3, 85748, Garching, Germany.
BMC Cancer. 2021 Sep 20;21(1):1041. doi: 10.1186/s12885-021-08776-7.
Individuals affected by cancer need to integrate this experience into their personal biography as their life continues after primary therapy, leading to substantial changes in self-perception. This study identified factors uniquely associated with 5 different cancer-related identities in order to improve the understanding of how self-perception in men affected by prostate cancer is associated with certain clinical and psychosocial characteristics.
In this cross-sectional study, long-term prostate cancer survivors after radical prostatectomy were asked to choose one of 5 cancer-related identities that described them best. Associations with sociodemographic, clinical, and psychological variables were investigated using multivariable logistic regression.
Three thousand three hundred forty-seven men (mean age 78.1 years) surveyed on average 15.6 years after prostatectomy were included. Most men favored the terms "someone who has had cancer" (43.9%) which was associated with a mild disease course, and "patient" (26.3%) which was associated with ongoing therapy and biochemical disease recurrence. The self-descriptions "cancer survivor" (16.8%), "cancer conqueror" (10.9%) and "victim" (2.1%) were less common. "Cancer survivor" was associated with high perceived disease severity (OR: 1.86 [1.44-2.40]). "Cancer survivor" and "cancer conqueror" were related to high benefit finding (OR: 1.89 [1.48-2.40], OR: 1.46 [1.12-1.89] respectively), and only "cancer conqueror" was associated with high well-being (OR: 1.84 [1.35-2.50]). Identification as "victim" was associated with a positive depression screening and low well-being (OR: 2.22 [1.15-4.31], OR: 0.38 [0.20-0.72] respectively) (all p < 0.05).
Although long-term survival is common among men affected by PCa, they display a large diversity in cancer-related identities, which are associated with unique clinical and psychological characteristics. These cancer-related identities and their distinctive properties are associated with psychological well-being even after a long follow-up.
癌症患者需要在原发性治疗后将这一经历融入个人传记中，从而导致自我认知的重大变化。本研究旨在确定与 5 种不同癌症相关身份相关的独特因素，以提高对前列腺癌男性患者自我认知与某些临床和心理社会特征之间关联的理解。
在这项横断面研究中，接受根治性前列腺切除术的长期前列腺癌幸存者被要求选择最能描述自己的 5 种癌症相关身份之一。使用多变量逻辑回归分析与社会人口学、临床和心理变量的关联。
3347 名平均在前列腺癌根治术后 15.6 年接受调查的男性患者被纳入研究。大多数男性选择了“曾患癌症的人”（43.9%），这与疾病轻度病程相关；选择了“患者”（26.3%），这与持续治疗和生化疾病复发相关。自我描述为“癌症幸存者”（16.8%）、“癌症征服者”（10.9%）和“受害者”（2.1%）的比例较低。“癌症幸存者”与高疾病严重程度感知相关（OR：1.86[1.44-2.40]）。“癌症幸存者”和“癌症征服者”与高益处发现相关（OR：1.89[1.48-2.40]，OR：1.46[1.12-1.89]），只有“癌症征服者”与高幸福感相关（OR：1.84[1.35-2.50]）。将自己认定为“受害者”与抑郁筛查阳性和幸福感低相关（OR：2.22[1.15-4.31]，OR：0.38[0.20-0.72]）（均 p<0.05）。
尽管长期生存在前列腺癌患者中很常见，但他们表现出与独特的临床和心理社会特征相关的癌症相关身份的多样性。这些癌症相关身份及其独特特征与心理幸福感相关，即使在长期随访后也是如此。
