Costello M W, Rigilano J C
Department of Family Practice, Malcolm Grow USAF Medical Center, Andrews AFB, MD 20331.
Fam Pract Res J. 1986 Spring;5(3):177-89.
To determine the percentage of acute myocardial infarction patients suitable for streptokinase thrombolysis, the charts of 990 patients from four separate hospitals with a discharge diagnosis of acute myocardial infarction were studied. In all, 750 were confirmed to actually have suffered acute myocardial infarction by enzyme and electrocardiogram criteria. Of these, 233 (31 percent of all patients with acute myocardial infarction) were judged to be suitable streptokinase candidates by virtue of being 75 years of age or younger, showing evidence of acute transmural infarction, having no contraindications to anticoagulation, and presenting to the Emergency Room within six hours or less after onset of chest pain. It is concluded that approximately one-third of all acute myocardial infarction patients in this population were eligible for streptokinase thrombolysis and that there is therefore a significant continuing role for traditional acute myocardial infarction management.
为确定适合链激酶溶栓治疗的急性心肌梗死患者的比例，研究了来自四家不同医院的990例出院诊断为急性心肌梗死患者的病历。总共750例经酶学和心电图标准确诊为实际发生急性心肌梗死。其中，233例（占所有急性心肌梗死患者的31%）因年龄在75岁及以下、有急性透壁梗死证据、无抗凝禁忌证且在胸痛发作后6小时或更短时间内就诊于急诊室，被判定为适合使用链激酶的患者。得出的结论是，该人群中约三分之一的急性心肌梗死患者符合链激酶溶栓治疗条件，因此传统的急性心肌梗死治疗仍有重要的持续作用。
