Sholler G F, Celermajer J M, Whight C M, Bauman A E
Adolph Basser Institute of Cardiology, Children's Hospital, Camperdown, Sydney, Australia.
Am J Cardiol. 1987 Nov 1;60(13):1112-6. doi: 10.1016/0002-9149(87)90363-8.
In a study of 38 normal infants, serial measurements of systemic (n = 169) and pulmonary (n = 143) blood flow were undertaken from the ages of 2 weeks to 12 months by 2-dimensional, M-mode and pulsed Doppler echocardiography. Cardiac output changed linearly (cardiac output = 0.3 X height -0.99 liter/min), and cardiac index was validated as a means for standardizing cardiac output in infants younger than 10 to 13 months of age. Infants younger than 2 months had lower cardiac indexes and stroke volume indexes (2.6 +/- 0.7 liters/min/m2 and 19 +/- 5 ml/m2, respectively) compared with those aged 12 months (3.2 +/- 0.7 liter/min/m2 and 25 +/- 5 ml/m2, respectively). Changes in cardiac output in individual infants over time suggest nonmorphometric modulating factors for cardiovascular function.
在一项针对38名正常婴儿的研究中，采用二维、M型和脉冲多普勒超声心动图，从2周龄至12月龄对169例体循环血流量和143例肺循环血流量进行了连续测量。心输出量呈线性变化（心输出量=0.3×身高-0.99升/分钟），并且心脏指数被证实是一种标准化10至13月龄以下婴儿心输出量的方法。与12月龄婴儿（分别为3.2±0.7升/分钟/平方米和25±5毫升/平方米）相比，2月龄以下婴儿的心脏指数和每搏量指数较低（分别为2.6±0.7升/分钟/平方米和19±5毫升/平方米）。个体婴儿的心输出量随时间的变化提示了心血管功能的非形态学调节因素。
