School of Public Health, University of California Berkeley, Berkeley, California.
School of Medicine, University of California Riverside, Riverside, California.
J Am Acad Dermatol. 2022 Feb;86(2):399-405. doi: 10.1016/j.jaad.2021.09.018. Epub 2021 Sep 20.
Lower socioeconomic position usually portends worse health outcomes, but multiple studies have found that atopic dermatitis is associated with higher socioeconomic position. The nature of this relationship remains unclear.
To systematically review the literature on socioeconomic position and atopic dermatitis and determine whether the association varies by patient or study characteristics.
A literature search was conducted in the PubMed and Embase databases. Individual-level studies addressing the association between all measures of socioeconomic position and the prevalence or incidence of atopic dermatitis were eligible for inclusion. Two independent reviewers screened all texts and extracted all data for qualitative synthesis.
Eighty-eight studies met the inclusion criteria. Of the 88 studies, 42% (37) found a positive association between atopic dermatitis and socioeconomic position, 15% (13) found a negative association, and 43% (38) found a null or inconsistent association. Studies conducted in Europe, among children, and based on self-report of eczema were more likely to find a positive association with socioeconomic position.
Studies varied both in terms of the measurement of socioeconomic position and the definition of atopic dermatitis, limiting quantitative synthesis.
The evidence of a positive association between atopic dermatitis and socioeconomic position is not consistent.
较低的社会经济地位通常预示着更糟糕的健康结果,但多项研究发现特应性皮炎与较高的社会经济地位有关。这种关系的性质尚不清楚。
系统回顾有关社会经济地位和特应性皮炎的文献,并确定这种关联是否因患者或研究特征而有所不同。
在 PubMed 和 Embase 数据库中进行了文献检索。符合纳入标准的研究为个体水平研究,其内容涉及所有社会经济地位衡量指标与特应性皮炎的患病率或发病率之间的关联。两名独立审查员筛选了所有文本并提取了所有数据进行定性综合分析。
符合纳入标准的研究有 88 项。在这 88 项研究中,42%(37 项)发现特应性皮炎与社会经济地位之间存在正相关,15%(13 项)发现负相关,43%(38 项)发现无关联或关联不一致。在欧洲进行的、针对儿童的、基于自我报告的湿疹的研究更有可能发现与社会经济地位之间存在正相关。
研究在社会经济地位的衡量和特应性皮炎的定义方面存在差异,限制了定量综合分析。
特应性皮炎与社会经济地位之间存在正相关的证据并不一致。