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2013-2016 年埃塞俄比亚婴儿肠套叠的流行病学。

Epidemiology of intussusception among infants in Ethiopia, 2013-2016.

机构信息

Department of Surgery, Addis Ababa University, Addis Ababa, Ethiopia.

World Health Organization, Ethiopia Country Office, Addis Ababa, Ethiopia.

出版信息

Pan Afr Med J. 2021 Jul 27;39(Suppl 1):2. doi: 10.11604/pamj.supp.2021.39.1.21299. eCollection 2021.

DOI:10.11604/pamj.supp.2021.39.1.21299
PMID:34548894
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8437422/
Abstract

INTRODUCTION

intussusception is a condition in which one segment of the bowel prolapses into another causing obstruction. Information on the epidemiology of intussusception in sub-Saharan Africa is limited. We describe the sociodemographic and clinical characteristics of children with intussusception in Ethiopia.

METHODS

active surveillance for children < 12 months of age with intussusception was conducted at six sentinel hospitals in Ethiopia. Limited socio-economic and clinical data were collected from enrolled children. Characteristics among children who died and children who survived were compared using the Wilcoxon rank sum test for continuous variables and Chi-square tests for categorical variables.

RESULTS

total of 164 children < 12 months of age with intussusception were enrolled; 62% were male. The median age at symptom onset was 6 months with only 12 (7%) of cases occurring in the first 3 months of life. Intussusception was reduced by surgery in 90% of cases and 10% were reduced by enema; 13% of cases died. Compared to survivors, children who died had a significantly longer time to presentation to the first health care facility and to the treating health care facility (median 3 days versus 2 days, p = 0.02, respectively).

CONCLUSION

the high mortality rate, late presentation of intussusception cases, and lack of modalities for non-surgical management at some facilities highlight the need for better management of intussusception cases in Ethiopia.

摘要

介绍

肠套叠是一段肠管套入其相连的肠管腔内引起梗阻的一种疾病。撒哈拉以南非洲地区肠套叠的流行病学信息有限。我们描述了埃塞俄比亚肠套叠患儿的社会人口学和临床特征。

方法

在埃塞俄比亚的六家哨点医院对 12 个月以下患有肠套叠的儿童进行主动监测。从入组儿童中收集有限的社会经济和临床数据。使用 Wilcoxon 秩和检验比较连续变量和卡方检验比较分类变量,比较死亡和存活儿童的特征。

结果

共纳入 164 名 12 个月以下患有肠套叠的儿童,其中 62%为男性。症状发作的中位年龄为 6 个月,只有 12 例(7%)发生在生命的头 3 个月。90%的病例通过手术复位,10%的病例通过灌肠复位;13%的病例死亡。与存活者相比,死亡者首次就诊于第一家医疗机构和治疗医疗机构的时间明显延长(中位数分别为 3 天和 2 天,p = 0.02)。

结论

高死亡率、肠套叠病例就诊时间晚以及一些医疗机构缺乏非手术治疗手段,突显了埃塞俄比亚需要更好地管理肠套叠病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab56/8437422/ccf7ef8c7795/PAMJ-SUPP-39-1-2-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab56/8437422/d11349ec98b8/PAMJ-SUPP-39-1-2-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab56/8437422/ccf7ef8c7795/PAMJ-SUPP-39-1-2-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab56/8437422/d11349ec98b8/PAMJ-SUPP-39-1-2-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab56/8437422/ccf7ef8c7795/PAMJ-SUPP-39-1-2-g002.jpg

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