红核的神经化学意义。
Neurochemical significance of the red nucleus.
作者信息
Nieto D, Nieto A
机构信息
Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, D.F.
出版信息
Bull Clin Neurosci. 1986;51:89-93.
This study reviews some of the more prominent reports related to neuromelanin and the physiological significance of the substantia nigra and the red nucleus. The phylogenetic and ontogenetic parallelism between these two structures is considered. The presence of dopachrome in the red nucleus and of neuromelanin in the substantia nigra is discussed. An experimental study in four human brains in which the red nucleus was injected with zinc sulfate showed the presence of neuromelanin in the red nucleus. This is the first reported demonstration that dopachrome present in the red nucleus is the precursor of neuromelanin.
本研究回顾了一些与神经黑色素以及黑质和红核的生理意义相关的更突出的报告。考虑了这两个结构之间的系统发生和个体发生的平行性。讨论了红核中多巴色素的存在以及黑质中神经黑色素的存在。在四例人脑的实验研究中，向红核注射硫酸锌，结果显示红核中存在神经黑色素。这是首次报道证明红核中存在的多巴色素是神经黑色素的前体。
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