Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Acta Paediatr. 2022 Jan;111(1):17-23. doi: 10.1111/apa.16121. Epub 2021 Oct 2.
Children born with univentricular hearts undergo staged surgical procedures to a Fontan circulation. Long-term experience with Fontan palliation has shown dramatically improved survival but also of a life-long burden of an abnormal circulation with significant morbidity. Many Fontan patients have reduced exercise capacity, oxygen uptake, lung function and quality of life. Endurance training may improve submaximal, but not maximal, exercise capacity, lung function and quality of life. Physical activity and endurance training is also positively correlated with sleep quality. Reviewing the literature and from our single-centre experience, we believe there is enough evidence to support structured individualised endurance training in most young Fontan patients.
患有单心室心脏的儿童需要进行分期手术，以建立 Fontan 循环。Fontan 姑息疗法的长期经验表明，生存率显著提高，但异常循环的终身负担也很大，发病率很高。许多 Fontan 患者的运动能力、摄氧量、肺功能和生活质量降低。耐力训练可以提高次最大运动能力，但不能提高最大运动能力、肺功能和生活质量。身体活动和耐力训练也与睡眠质量呈正相关。通过对文献的回顾和我们单中心的经验，我们相信有足够的证据支持对大多数年轻的 Fontan 患者进行个体化的耐力训练。
