Ding Xiaodan, Crawford Adam W, Derrick William P, Unruh Daniel K, Groeneman Ryan H, Hutchins Kristin M
Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas, 79409, USA.
Department of Biological Sciences, Webster University, St. Louis, Missouri, 63119, USA.
Chemistry. 2021 Nov 25;27(66):16329-16333. doi: 10.1002/chem.202102833. Epub 2021 Oct 12.
The solution and mechanochemical synthesis of two cocrystals that differ in the stoichiometric ratio of the components (stoichiometric cocrystals) is reported. The components in the stoichiometric cocrystals interact through hydrogen or hydrogen/halogen bonds and differ in π-stacking arrangements. The difference in structure and noncovalent interactions affords dramatically different thermal expansion behaviors in the two cocrystals. At certain molar ratios, the cocrystals are obtained concomitantly; however, by varying the ratios, a single stoichiometric cocrystal is achieved using mechanochemistry.
报道了两种在组分化学计量比上不同的共晶体（化学计量共晶体）的溶液法和机械化学合成。化学计量共晶体中的组分通过氢键或氢/卤键相互作用，并且在π-堆积排列上有所不同。结构和非共价相互作用的差异使得两种共晶体具有截然不同的热膨胀行为。在某些摩尔比下，可同时获得共晶体；然而，通过改变比例，利用机械化学可得到单一的化学计量共晶体。
