用于卡那霉素的信号关闭光电流型适体传感器：链置换反应结合 p-n 竞争。
Signal-off photoelectrochemical aptasensor for kanamycin: Strand displacement reaction combines p-n competition.
机构信息
College of Chemistry, Green Catalysis Center, Zhengzhou University, Zhengzhou, 450001, PR China.
Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450001, PR China.
出版信息
Anal Chim Acta. 2021 Oct 9;1181:338927. doi: 10.1016/j.aca.2021.338927. Epub 2021 Aug 11.
A"signal-off" photoelectrochemical aptasensor based on p-n type semiconductor competitive quenching effect and strand displacement reaction was constructed for the determination of kanamycin. Au NPs@MgInS-graphene composite was used as n-type photoactive semiconductor material. In the presence of the kanamycin, strand displacement reaction was triggered and the p-type CuInS quantum dots labeled aptamer was introduced on the Au NPs@MgInS-graphene surface. The CuInS quantum dots can competitive consume the electron donors (AA) and light energy of the PEC system, thus quenched the anodic photocurrent of Au NPs@MgInS-graphene. The photocurrent decreased with the increase of kanamycin concentration. The linear range of kanamycin was 1.0 pM-10 μM, and the detection limit was 1.7 pM. In addition, the method can be used for the determination of kanamycin in milk and honey.
一种基于 p-n 型半导体竞争猝灭效应和链置换反应的“信号关闭”光电化学适体传感器被构建用于卡那霉素的测定。Au NPs@MgInS-石墨烯复合材料被用作 n 型光活性半导体材料。在存在卡那霉素的情况下，触发链置换反应，并且将标记有适体的 p 型 CuInS 量子点引入 Au NPs@MgInS-石墨烯表面。CuInS 量子点可以竞争性地消耗电子给体 (AA) 和 PEC 系统的光能，从而猝灭 Au NPs@MgInS-石墨烯的阳极光电流。光电流随着卡那霉素浓度的增加而降低。卡那霉素的线性范围为 1.0 pM-10 μM，检测限为 1.7 pM。此外，该方法可用于牛奶和蜂蜜中卡那霉素的测定。
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