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脐带血血小板凝胶在伴有肌腱外露的糖尿病足管理中的作用。

The role of cord blood platelet gel in the management of a diabetic foot with tendon exposure.

机构信息

Unit of Vascular & Endovascular Surgery, Grande Ospedale Metropolitano "Bianchi-Melacrino-Morelli", Reggio Calabria, 89124, Italy.

Calabria Cord Blood Bank, Service of Immunohaematology & Transfusion Medicine, Grande Ospedale Metropolitano "Bianchi-Melacrino-Morelli", Reggio Calabria, 89214, Italy.

出版信息

Regen Med. 2021 Nov;16(12):1051-1056. doi: 10.2217/rme-2021-0044. Epub 2021 Sep 24.

Abstract

Diabetic foot infection is frequent in diabetic patients and is due to neuropathy, trauma or peripheral arterial disease. The presence of an abscess requires urgent drainage and specific antibiotic therapy. Patients with critical limb ischemia need revascularization and, subsequently the intervention of a plastic surgeon is often required in cases of exposure of tendons and ligaments. During the COVID-19 pandemic, a patient was refered to our department with an abscess on the dorsum of the left foot. After urgent drainage with tendon exposure, he started specific antibiotic therapy and underwent tibial vessels angioplasty. After infection healing cord blood platelet gel was applied, accelerating the healing process, with injection of its liquid part into the exposed tendons, thus retaining the vital functions of the tendons.

摘要

糖尿病患者常发生足部感染,其病因包括神经病变、创伤或外周动脉疾病。脓肿的出现需要紧急引流和特定的抗生素治疗。伴有严重肢体缺血的患者需要进行血运重建,随后常需要整形外科医生的干预,以处理肌腱和韧带外露的情况。在 COVID-19 大流行期间,有一位患者因左足背部脓肿被转至我科。在肌腱暴露后进行紧急引流后,他开始接受特定的抗生素治疗,并进行了胫骨血管成形术。感染愈合后,应用了脐带血血小板凝胶,加速了愈合过程,并将其液体部分注入暴露的肌腱中,从而保留了肌腱的重要功能。

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