Grupo AUNA, Instituto de Cancerología Las Américas, Medellín, Colombia.
Facultad de Medicina, Universidad Pontificia Bolivariana, Medellín, Colombia.
Biomedica. 2021 Sep 22;41(3):396-402. doi: 10.7705/biomedica.5430.
Histiocytosis comprises a heterogeneous group of inflammatory diseases whose main cellular components are dendritic cells and macrophages. The inflammatory infiltrate can affect the skin and other organs and the clinical outcome varies from mild to fatal depending on the involved cell subset and multisystemic compromise. Delay in diagnosis may occur due to its non-specific presentation and to a low suspicion on the part of the clinician. We report the case of an infant who despite multiple consultations with nonspecific but characteristic symptoms of the disease was only finally diagnosed thanks to histopathological findings.
组织细胞增生症是一组异质性炎症性疾病，其主要细胞成分是树突状细胞和巨噬细胞。炎症浸润可累及皮肤和其他器官，临床结局因受累细胞亚群和多系统受累的不同而有所差异。由于其表现不具特异性且临床医生警惕性低，可能会导致诊断延误。我们报告了一例婴儿病例，尽管多次就诊，但由于疾病具有非特异性但特征性的症状，最终仅通过组织病理学发现才得以确诊。
