Azevedo Ricardo B R, Olofsson Peter
Department of Biology and Biochemistry, University of Houston, Houston, TX, USA.
Department of Mathematics, Physics and Chemical Engineering, Jönköping University, Sweden.
Math Biosci. 2021 Nov;341:108708. doi: 10.1016/j.mbs.2021.108708. Epub 2021 Sep 22.
Evolutionary rescue is the process whereby a declining population may start growing again, thus avoiding extinction, via an increase in the frequency of fitter genotypes. These genotypes may either already be present in the population in small numbers, or arise by mutation as the population declines. We present a simple two-type discrete-time branching process model and use it to obtain results such as the probability of rescue, the shape of the population growth curve of a rescued population, and the time until the first rescuing mutation occurs. Comparisons are made to existing results in the literature in cases where both the mutation rate and the selective advantage of the beneficial mutations are small.
进化拯救是指一个数量下降的种群通过更适应环境的基因型频率增加,从而再次开始增长并避免灭绝的过程。这些基因型可能已少量存在于种群中,或者在种群数量下降时通过突变产生。我们提出了一个简单的两类离散时间分支过程模型,并利用它得出诸如拯救概率、获救种群的种群增长曲线形状以及首次出现拯救性突变的时间等结果。在有益突变的突变率和选择优势都较小的情况下,我们将所得结果与文献中的现有结果进行了比较。