Sharma Jyoti, Gupta Kanupriya, Schwebke Jane R, Geisler William M, Muzny Christina A
From the Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL.
Sex Transm Dis. 2022 Mar 1;49(3):e53-e55. doi: 10.1097/OLQ.0000000000001564.
We adapted a simple hydroxylamine-based indole assay to detect indole from stored vaginal swab specimens from women with and without bacterial vaginosis (BV). Women with BV had significantly higher vaginal indole levels compared with women without BV (6451.5 vs 5632.4 μM; P = 0.01), suggesting that indole-producing bacteria are a component of BV.
我们采用了一种基于羟胺的简单吲哚检测方法,以检测患有和未患有细菌性阴道病(BV)的女性储存阴道拭子标本中的吲哚。与未患BV的女性相比,患BV的女性阴道吲哚水平显著更高(6451.5对5632.4 μM;P = 0.01),这表明产吲哚细菌是BV的一个组成部分。