在过敏致敏期增加玉米油的摄入量会加重口服过敏原暴露后的食物过敏严重程度。
Increased corn oil intake during an allergy sensitization period aggravates food allergy severity after oral allergen exposure.
机构信息
Department of Food Science and Nutrition, School of Food Science and Nutrition, Mukogawa Women's University, Hyogo, Japan.
出版信息
Biosci Biotechnol Biochem. 2021 Oct 21;85(11):2322-2325. doi: 10.1093/bbb/zbab164.
PMID:34562086
Abstract
Egg white (EW) allergy model mice underwent 15-day oral immunotherapy (OIT) using diets with different corn-oil content and 1% EW. After OIT, mortality following an oral food challenge in OIT groups was approximately 90%. However, in previous studies, mortality was 0%. This phenomenon is to be associated with increased corn-oil intake during allergy sensitization and allergen exposure for 2 weeks.
摘要
蛋清（EW）过敏模型小鼠接受了为期 15 天的口服免疫治疗（OIT），使用不同玉米油含量和 1% EW 的饮食。OIT 后，OIT 组口服食物挑战后的死亡率约为 90%。然而，在之前的研究中，死亡率为 0%。这种现象与过敏致敏和过敏原暴露 2 周期间玉米油摄入量增加有关。
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