Kenyon E, Polse K A, Seger R G
Ophthalmology. 1986 Feb;93(2):231-6. doi: 10.1016/s0161-6420(86)33768-0.
The effect of wearing schedule on extended-wear (EW) success was evaluated over a nine-month period by assigning 36 subjects to 5 different wearing schedules (removal every 4, 7, 14, or 28 days, or daily wear [DW]). All but one EW patient required interruption of extended wear at least once; half of the DW patients completed the study without interruption. The most prevalent (100%) complication in the EW group was epithelial microcysts; 54% had to discontinue EW for 67 +/- 30 days while severe microcysts subsided. Evidence is given for a hypoxic etiology of microcysts. Other EW complications included: persistent punctate keratitis, infiltrative keratitis, infection, and idiopathic red eye. Neither the level of overnight corneal swelling nor the period between removals influenced the incidence or severity of complications. Data is given on the recovery of corneal parameters after EW is discontinued.
通过将36名受试者分配到5种不同的佩戴时间表（每4天、7天、14天或28天摘除，或每日佩戴[DW]），在九个月的时间里评估了佩戴时间表对长戴型（EW）成功率的影响。除一名EW患者外，所有患者至少需要中断一次长戴；一半的DW患者未中断地完成了研究。EW组中最常见（100%）的并发症是上皮微囊肿；54%的患者不得不中断EW 67±30天，直到严重的微囊肿消退。有证据表明微囊肿的病因是缺氧。其他EW并发症包括：持续性点状角膜炎、浸润性角膜炎、感染和特发性红眼。过夜角膜肿胀程度和摘除间隔时间均未影响并发症的发生率或严重程度。给出了EW停止后角膜参数恢复的数据。
