2014-2018 年住院患者尿培养结果分析：病原菌分布及药敏情况
Urine Culture in Hospitalized Patients during 2014-2018: An Analysis on Pathogen Distribution and Drug Sensitivity.
机构信息
Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China.
Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University, Qingdao 266003, China.
出版信息
Dis Markers. 2021 Sep 15;2021:6646024. doi: 10.1155/2021/6646024. eCollection 2021.
OBJECTIVE
We sought to analyze the distribution and antibiotic sensitivity of pathogens in hospitalized patients and to provide a scientific reference for the rational application of antibiotics.
METHODS
From January 2014 to December 2018, urine cultures from patients in our hospital were collected and analyzed retrospectively for the presence, distribution, and drug sensitivity of pathogens.
RESULTS
A total of 42,854 midstream urine cultures were collected from which 11,891 (27.75%) pathogens were isolated, including 8101 (68.13%) strains of gram-negative bacteria, 2580 (21.69%) strains of gram-positive bacteria, and 1210 (10.18%) strains of fungi. and were the most common species of gram-negative and gram-positive bacteria, respectively. Drug sensitivity varied among different pathogens. Clear drug resistance was observed in bacteria, while fungus exhibited relatively lower resistance.
CONCLUSION
Pathogens responsible for urinary tract infections in hospitalized patients are diversiform and display resistance to some antibiotics. Drug resistance monitoring should be enhanced to optimize antimicrobial therapy.
目的
分析住院患者病原菌分布及药敏情况，为临床合理应用抗生素提供科学参考。
方法
回顾性分析 2014 年 1 月至 2018 年 12 月我院住院患者中段尿培养病原菌的分布及药敏情况。
结果
共收集 42854 份中段尿培养，分离出病原菌 11891 株，检出率为 27.75%，其中革兰阴性菌 8101 株占 68.13%，革兰阳性菌 2580 株占 21.69%，真菌 1210 株占 10.18%。大肠埃希菌和肺炎克雷伯菌是革兰阴性菌和革兰阳性菌中最常见的菌种。不同病原菌对抗菌药物的敏感性存在差异，细菌耐药情况较严重，真菌耐药率相对较低。
结论
住院患者尿路感染病原菌种类多样，存在部分耐药情况，应加强耐药监测，优化抗菌药物治疗方案。
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