Jehn U W, Mempel M A
Blut. 1986 Mar;52(3):165-8. doi: 10.1007/BF00320532.
A patient with acute myelomonocytic leukemia who experienced a spontaneous remission, is reported. He had precedent and concurrent bacterial infections as most of these cases described. Low peripheral WBC and myeloblasts, Auer-rod positive blasts, bone marrow eosinophilia with atypical eosinophils, and a partial deletion of chromosome 16 were favorable prognostic parameters. A brief review of the literature and possible explanations for the regulation of granulopoiesis are presented.
报告了1例急性粒单核细胞白血病自发缓解的患者。与大多数此类病例描述的情况一样,他有既往和并发的细菌感染。外周血白细胞和原始粒细胞数量低、Auer小体阳性的原始细胞、伴有非典型嗜酸性粒细胞的骨髓嗜酸性粒细胞增多以及16号染色体部分缺失是有利的预后参数。本文对相关文献进行了简要综述,并提出了粒细胞生成调节的可能解释。