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急性髓系白血病的自发缓解。1例报告及文献简要综述。

Spontaneous remission of acute myeloid leukemia. A report of a case and brief review of the literature.

作者信息

Jehn U W, Mempel M A

出版信息

Blut. 1986 Mar;52(3):165-8. doi: 10.1007/BF00320532.

DOI:10.1007/BF00320532
PMID:3456806
Abstract

A patient with acute myelomonocytic leukemia who experienced a spontaneous remission, is reported. He had precedent and concurrent bacterial infections as most of these cases described. Low peripheral WBC and myeloblasts, Auer-rod positive blasts, bone marrow eosinophilia with atypical eosinophils, and a partial deletion of chromosome 16 were favorable prognostic parameters. A brief review of the literature and possible explanations for the regulation of granulopoiesis are presented.

摘要

报告了1例急性粒单核细胞白血病自发缓解的患者。与大多数此类病例描述的情况一样,他有既往和并发的细菌感染。外周血白细胞和原始粒细胞数量低、Auer小体阳性的原始细胞、伴有非典型嗜酸性粒细胞的骨髓嗜酸性粒细胞增多以及16号染色体部分缺失是有利的预后参数。本文对相关文献进行了简要综述,并提出了粒细胞生成调节的可能解释。

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本文引用的文献

1
The treatment of malignant tumors by bacterial toxins as developed by the late William B. Coley, M.D., reviewed in the light of modern research.已故医学博士威廉·B·科利研发的用细菌毒素治疗恶性肿瘤的方法,根据现代研究进行综述。
Cancer Res. 1946 Apr;6:205-16.
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The natural history of untreated acute leukemia.未经治疗的急性白血病的自然病程。
Ann N Y Acad Sci. 1954 Dec 6;60(2):322-58. doi: 10.1111/j.1749-6632.1954.tb40023.x.
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Effects of concurrent infections and their toxins on the course of leukemia.合并感染及其毒素对白血病病程的影响。
Acta Med Scand Suppl. 1958;338:1-47.
4
Effects of glandular fever infection in acute leukaemia.腺热感染在急性白血病中的影响。
Br Med J. 1953 Mar 14;1(4810):589-93. doi: 10.1136/bmj.1.4810.589.
5
Acute nonlymphoblastic leukemia: prognostic factors in adults with long-term follow-up.急性非淋巴细胞白血病:长期随访的成人患者的预后因素
Cancer. 1982 Oct 15;50(8):1462-71. doi: 10.1002/1097-0142(19821015)50:8<1462::aid-cncr2820500804>3.0.co;2-1.
6
[Spontaneous remission of acute leukemia in 2 children (author's transl)].2例儿童急性白血病的自发缓解(作者译)
Arch Fr Pediatr. 1981 Apr;38(4):275-6.
7
Evidence for the separate human T-lymphocyte subpopulations that collaborate with autologous monocyte/macrophages in the elaboration of colony-stimulating activity and those that suppress this collaboration.
Blood. 1983 Nov;62(5):1088-99.
8
A pericentric inversion of chromosome 16 is associated with dysplastic marrow eosinophils in acute myelomonocytic leukemia.16号染色体的臂间倒位与急性粒单核细胞白血病中发育异常的骨髓嗜酸性粒细胞有关。
Blood. 1984 Apr;63(4):800-2.
9
Prognostic value of cytologic parameters in acute myelogenous leukemia.急性髓性白血病细胞学参数的预后价值
Cancer. 1984 Apr 1;53(7):1526-32. doi: 10.1002/1097-0142(19840401)53:7<1526::aid-cncr2820530718>3.0.co;2-2.
10
Association of an inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia. A unique cytogenetic-clinicopathological association.16号染色体倒位与急性粒单核细胞白血病异常骨髓嗜酸性粒细胞的关联。一种独特的细胞遗传学 - 临床病理关联。
N Engl J Med. 1983 Sep 15;309(11):630-6. doi: 10.1056/NEJM198309153091103.