Sandberg A A, Gibas Z, Saren E, Li F P, Limon J, Tebbi C K
Cancer Genet Cytogenet. 1986 May;22(1):55-61. doi: 10.1016/0165-4608(86)90137-8.
Two histologically benign adipose tumors were found to have clonal karyotypic changes. Del(4), del(6), and inv(13) were present in a fibrolipoma, and t(7;8) in a lipoblastoma. Additional studies are needed of the frequency and malignant potential of lipomas with cytogenetic abnormalities.
发现两例组织学上为良性的脂肪肿瘤存在克隆性核型改变。在一例纤维脂肪瘤中存在4号染色体缺失（del(4)）、6号染色体缺失（del(6)）和13号染色体倒位（inv(13)），在一例成脂肪细胞瘤中存在7号与8号染色体易位（t(7;8)）。需要对具有细胞遗传学异常的脂肪瘤的发生率和恶性潜能进行更多研究。
