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估算希腊与房颤相关的卒中的经济负担。

Estimation of the economic burden of atrial fibrillation-related stroke in Greece.

机构信息

Hellenic Stroke Organization, Athens, Greece.

Pfizer Hellas, Athens, Greece.

出版信息

Expert Rev Pharmacoecon Outcomes Res. 2022 Apr;22(3):429-435. doi: 10.1080/14737167.2021.1979961. Epub 2021 Sep 26.

Abstract

BACKGROUND

Stroke is aleading cause of death and disability, with atrial fibrillation (AF) being among key risk factors and AF-related stroke inflicting significant burden on healthcare systems and society. The present study was undertaken for estimating the total annual socioeconomic burden of AF-related stroke in Greece and identifying the key cost contributors.

RESEARCH DESIGN AND METHODS

A cost-of-illness model was developed for estimating the total annual economic burden of AF-related stroke in Greece, from asocietal perspective (year 2018). Atargeted literature review and an advisory board consisting of key experts in the management of AF and AF-related stroke were performed for collecting local resource use and epidemiological data.

RESULTS

The total annual socioeconomic burden of AF-related stroke was estimated at €175million, in 2018. Direct and indirect costs accounted for 59% and 41%, respectively. Main contributors were informal care (21.1%), patients' productivity losses (19.7%) and hospitalizations (15.0%), accounting for more than half of the total costs of AF-related stroke events. A F-related stroke imposes asignificant socioeconomic burden in Greece. Despite results relying on estimations, it seems that ensuring efficient reallocation of resources in appropriate prevention and early intervention strategies could decrease AF-related stroke's burden but also enhance healthcare systems' efficiency.

ABBREVIATIONS

AF=atrial fibrillation.

摘要

背景

中风是导致死亡和残疾的主要原因,其中心房颤动(AF)是关键的风险因素之一,AF 相关的中风给医疗保健系统和社会带来了巨大的负担。本研究旨在估计希腊 AF 相关中风的总年度社会经济负担,并确定关键的成本贡献者。

研究设计和方法

从社会角度(2018 年)开发了一个疾病成本模型,以估计希腊 AF 相关中风的总年度经济负担。进行了针对性的文献回顾和由 AF 和 AF 相关中风管理方面的主要专家组成的顾问委员会,以收集当地的资源利用和流行病学数据。

结果

2018 年,AF 相关中风的总年度社会经济负担估计为 1.75 亿欧元。直接成本和间接成本分别占 59%和 41%。主要贡献者是非正式护理(21.1%)、患者生产力损失(19.7%)和住院治疗(15.0%),占 AF 相关中风事件总费用的一半以上。AF 相关中风在希腊造成了巨大的社会经济负担。尽管结果依赖于估计,但似乎通过有效重新分配资源,制定适当的预防和早期干预策略,可能会降低 AF 相关中风的负担,同时提高医疗保健系统的效率。

缩写词

AF=心房颤动。

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