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体重≤1000克婴儿先天性和后天性心脏缺陷的经皮心脏介入治疗的可行性和安全性

Feasibility and Safety of Percutaneous Cardiac Interventions for Congenital and Acquired Heart Defects in Infants ≤1000 g.

作者信息

Philip Ranjit, Towbin Jeffrey, Tailor Neil, Joshi Vijaya, Johnson Jason N, Naik Ronak, Waller B Rush, Sathanandam Shyam

机构信息

Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.

The Heart Institute, Le Bonheur Children's Hospital, Memphis, TN 38103, USA.

出版信息

Children (Basel). 2021 Sep 21;8(9):826. doi: 10.3390/children8090826.

Abstract

The transcatheter closure of patent ductus arteriosus (TCPC) has been demonstrated to be feasible even in infants weighing ≤1000 g. However, other percutaneous cardiac interventions (PCI) for such small infants born with congenital heart defects (CHD) or acquired heart defects (AHD) have not been well described. The purpose of this study was to describe the feasibility and safety of PCI in infants ≤1000 g. A retrospective review was conducted between June 2015 and May 2021, looking at 148 consecutive PCIs performed on infants weighing ≤1000 g at the time of the procedure. The procedural success rate was 100%. The major adverse event (AE) rate for TCPC was 3%, while there were no major AEs for other PCI. It is feasible to perform PCIs in infants weighing ≤1000 g with CHD and AHD using currently available technologies.

摘要

经导管动脉导管未闭封堵术(TCPC)已被证明即使在体重≤1000克的婴儿中也是可行的。然而,对于患有先天性心脏病(CHD)或后天性心脏病(AHD)的此类小婴儿,其他经皮心脏介入治疗(PCI)尚未得到充分描述。本研究的目的是描述体重≤1000克婴儿进行PCI的可行性和安全性。对2015年6月至2021年5月期间进行的回顾性研究,观察了连续148例在手术时体重≤1000克的婴儿进行的PCI。手术成功率为100%。TCPC的主要不良事件(AE)发生率为3%,而其他PCI未发生主要不良事件。使用现有技术对体重≤1000克的CHD和AHD婴儿进行PCI是可行的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62b8/8465089/0c0de2473b9e/children-08-00826-g001.jpg

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