Christopher M M, Metz A L, Klausner J, Polzin D, Hayden D W
Vet Pathol. 1986 Mar;23(2):140-7. doi: 10.1177/030098588602300206.
A dog was presented with mandibular paralysis, photophobia, and diffuse atrophy of the cranial skeletal muscles. Physical examination also revealed glossal paralysis, reduction of the swallowing reflex, reduction of the pupillary light response, and generalized lymphadenopathy. Cytologic and ultrastructural examinations of blood films, bone marrow, and lymph node aspirates were consistent with acute myelomonocytic leukemia. Post-mortem examination revealed extensive, multisystemic neoplastic infiltration with marked involvement of the central and peripheral nervous systems, especially the cranial and lumbar spinal nerves and associated ganglia. Neurologic manifestations are unusual in acute myelomonocytic leukemia in the dog.
一只犬出现下颌麻痹、畏光和颅部骨骼肌弥漫性萎缩。体格检查还发现舌麻痹、吞咽反射减弱、瞳孔对光反应减弱和全身性淋巴结病。血液涂片、骨髓和淋巴结穿刺液的细胞学及超微结构检查结果与急性粒单核细胞白血病相符。尸检显示广泛的多系统肿瘤浸润，中枢和外周神经系统明显受累，尤其是颅神经和腰脊神经及相关神经节。在犬急性粒单核细胞白血病中，神经学表现并不常见。
