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人类感染:中欧意外蝇蛆病后烧伤创面感染的综述及首例报告

Human Infections by : A Mini-Review and the First Report of a Burn Wound Infection after Accidental Myiasis in Central Europe.

作者信息

Hladík Martin, Lipovy Bretislav, Kaloudova Yvona, Hanslianova Marketa, Vitkova Ivana, Deissova Tereza, Kempny Tomas, Svoboda Martin, Kala Zdenek, Brychta Pavel, Borilova Linhartova Petra

机构信息

Department of Burns and Plastic Surgery, Faculty of Medicine, Institution Shared with University Hospital Brno, Masaryk University, Jihlavská 20, 625 00 Brno, Czech Republic.

CEITEC-Central European Institute of Technology, Brno University of Technology, Purkyňova 656/123, 612 00 Brno, Czech Republic.

出版信息

Microorganisms. 2021 Sep 11;9(9):1934. doi: 10.3390/microorganisms9091934.

Abstract

are bacteria that cause rare infections, typically associated with the infestation of an open wound with fly larvae. Here, we present a unique case report of the first isolation from a burn wound with accidental myiasis in a 63-year-old homeless man and a literature review focused on human infections caused by these bacteria. So far, 23 cases of infection with have been reported; in 52% of these, larvae were found in the wound area. Most of these cases suffered from chronic non-healing wound infections but none of these were burn injuries. The overall fatality rate associated directly with in these cases was 17%. Infections with parasitic larvae occur in moderate climates (especially in people living in poor conditions); therefore, an infection with rare bacteria associated with accidental myiasis, such as , can be expected to become more common there. Thus, in view of the absence of recommendations regarding the treatment of patients with accidental myiasis and, therefore, the risk of infection with or other rare pathogens, we provide a list of recommendations for the treatment of such patients. The importance of meticulous microbial surveillance using molecular biological methods to facilitate the detection of rare pathogens is emphasized.

摘要

是引起罕见感染的细菌,通常与开放性伤口被蝇幼虫侵袭有关。在此,我们报告一例独特病例,首次从一名63岁无家可归男性的烧伤伤口伴意外蝇蛆病中分离出该菌,并对关于这些细菌引起的人类感染的文献进行综述。到目前为止,已报告23例感染病例;其中52%在伤口区域发现幼虫。这些病例大多患有慢性不愈合伤口感染,但均非烧伤。这些病例中与直接相关的总体死亡率为17%。寄生幼虫感染发生在温带气候地区(尤其是生活条件差的人群);因此,预计在这些地区,与意外蝇蛆病相关的罕见细菌感染,如,会变得更加常见。鉴于缺乏关于意外蝇蛆病患者治疗的建议,因此存在感染或其他罕见病原体的风险,我们提供了一份针对此类患者治疗的建议清单。强调了使用分子生物学方法进行细致微生物监测以促进罕见病原体检测的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a90/8465362/54962a43e5cf/microorganisms-09-01934-g001.jpg

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