Department of Interventional Radiology and Oncology, Tenon Hospital, Sorbonne Université, 75020 Paris, France.
Department of Radiology, Saint Antoine Hospital, Sorbonne Université, 75012 Paris, France.
Medicina (Kaunas). 2021 Aug 30;57(9):907. doi: 10.3390/medicina57090907.
Cancer-related vertebral compression fractures (VCF) may cause debilitating back pain and instability, affecting the quality of life of cancer patients. To further drive cement deposition during vertebroplasty, the aims of this restrospective case series study were to report the feasibility, safety and short term efficacy (≤6 months) of percutaneous vertebral fixation in cancer-related vertebral compression fractures using various intravertebral implants. All consecutive cancer patients treated with percutaneous vertebral fixation for VCF were retrospectively included. Various devices were inserted percutaneously under image guidance and filled by cement. Descriptive statistics were used and a matched paired analysis of pain scores was performed to assess for changes following interventions. A total of 18 consecutive patients (12 women (66.6%) and 6 men (33.3%); mean age 59.7 ± 15.5 years) were included. A total of 42 devices were inserted in 8 thoracic and 16 lumbar vertebrae. Visual analogue scale measurement significantly improved from 5.6 ± 1.8 preoperatively to 1.5 ± 1.7 at 1 week ( < 0.01) and to 1.5 ± 1.3 at 6 months ( < 0.01). No severe adverse events were observed, but three adjacent fractures occurred between 1 week and 5 months after implantation. Percutaneous vertebral fixation of cancer-related VCF is feasible and safe and allows pain relief.
癌症相关性椎体压缩性骨折（VCF）可引起严重的背痛和不稳定性，影响癌症患者的生活质量。为了进一步促进骨水泥在椎体成形术中的沉积，本回顾性病例系列研究旨在报告使用各种椎体内植入物经皮椎体固定治疗癌症相关性椎体压缩性骨折的可行性、安全性和短期疗效（≤6 个月）。
所有连续接受经皮椎体固定治疗 VCF 的癌症患者均被回顾性纳入研究。在影像引导下经皮插入各种器械，并填充骨水泥。采用描述性统计分析和疼痛评分的配对分析来评估干预后的变化。
共纳入 18 例连续患者（12 例女性（66.6%）和 6 例男性（33.3%）；平均年龄 59.7 ± 15.5 岁）。共在 8 个胸椎和 16 个腰椎中插入了 42 个器械。视觉模拟评分法（VAS）从术前的 5.6 ± 1.8 显著改善至术后 1 周的 1.5 ± 1.7（<0.01）和术后 6 个月的 1.5 ± 1.3（<0.01）。未观察到严重不良事件，但在植入后 1 周至 5 个月期间发生了 3 例相邻骨折。
经皮椎体固定治疗癌症相关性 VCF 是可行且安全的，并可缓解疼痛。
