用利妥昔单抗治疗副肿瘤性天疱疮：一例报告。
Therapy of paraneoplastic pemphigus with Rituximab: A case report.
机构信息
Department of Dermatology, Wuhan No. 1 Hospital, Wuhan, China.
School of Medicine, Jianghan University, Wuhan, China.
出版信息
Dermatol Ther. 2021 Nov;34(6):e15144. doi: 10.1111/dth.15144. Epub 2021 Oct 6.
PMID:34582076
Abstract
We report a case of 39-year-old female patient with paraneoplastic pemphigus (PNP) associated with thymoma treated with rituximab plus corticosteroids and methotrexate. After rituximab therapy for 8 weeks, oral ulcerations had cured, lesions on the trunk and limbs improved. Rituximab may be useful for PNP therapy, but further studies are necessary to confirm this hypothesis.
摘要
我们报告了一例 39 岁女性副肿瘤天疱疮（PNP）合并胸腺瘤患者，采用利妥昔单抗联合皮质类固醇和甲氨蝶呤治疗。利妥昔单抗治疗 8 周后，口腔溃疡已愈合，躯干和四肢的皮损改善。利妥昔单抗可能对 PNP 的治疗有效，但需要进一步的研究来证实这一假设。
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