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儿童患者新发肾上腺功能不全伴肾上腺危象

New-onset Adrenal Insufficiency Presenting with Adrenal Shock in a Pediatric Patient.

机构信息

LifePACT Critical Care Transport Team, Hasbro Children's Hospital, Providence, RI.

Division of Endocrinology, Department of Pediatrics, Warren Alpert Medical School of Brown University, Hasbro Children's Hospital, Providence, RI.

出版信息

R I Med J (2013). 2021 Oct 1;104(8):15-18.

Abstract

This case report describes new-onset adrenal insufficiency and adrenal shock in an 11-year-old male complaining of two weeks of malaise and weight loss. He was lethargic and pale in appearance. Work-up revealed hypoglycemia and hyponatremia without evidence for an infectious process. He was transported via a pediatric critical care transport team to a regional pediatric intensive care unit (PICU). He required intravenous fluids and vasopressors prior to arrival in the PICU. He had generalized weakness, and hyperpigmentation of his face and extremities. Adrenal insufficiency was suspected, and glucocorticoid administration led to improvement. Cortisol level was undetectable. At time of discharge, he was prescribed daily glucocorticoid and mineralocorticoid replacement, along with a stress dose glucocorticoid plan.

摘要

本病例报告描述了一名 11 岁男性出现新发肾上腺功能不全和肾上腺危象,该男性主诉两周来不适和体重减轻。他表现为昏睡和面色苍白。检查发现低血糖和低钠血症,无感染过程的证据。他由儿科危重病转运团队转运至区域性儿科重症监护病房(PICU)。在到达 PICU 之前,他需要静脉补液和血管加压素。他表现为全身无力,面部和四肢色素沉着。怀疑为肾上腺功能不全,给予糖皮质激素治疗后症状改善。皮质醇水平无法检测到。出院时,他被开具了每日糖皮质激素和盐皮质激素替代治疗,以及应激剂量糖皮质激素计划。

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