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术前背痛严重程度对微创经椎间孔腰椎椎间融合术(MIS-TLIF)后患者报告结局、恢复率及患者满意度的影响

The Effect of the Severity of Preoperative Back Pain on Patient-Reported Outcomes, Recovery Ratios, and Patient Satisfaction Following Minimally Invasive Transforaminal Lumbar Interbody Fusion (MIS-TLIF).

作者信息

Jacob Kevin C, Patel Madhav R, Parsons Alexander W, Vanjani Nisheka N, Pawlowski Hanna, Prabhu Michael C, Singh Kern

机构信息

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA.

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA.

出版信息

World Neurosurg. 2021 Dec;156:e254-e265. doi: 10.1016/j.wneu.2021.09.053. Epub 2021 Sep 25.

Abstract

BACKGROUND

Limited literature has addressed impact of preoperative back pain severity on patient-reported outcome measures (PROMs), recovery ratios (RRs), and patient satisfaction following minimally invasive transforaminal lumbar interbody fusion (MIS TLIF).

METHODS

MIS TLIFs were retrospectively identified and grouped: preoperative visual analog scale (VAS) back ≤7 or VAS back >7. PROMs, including PROMIS-PF, VAS back and leg, Oswestry Disability Index (ODI), and SF-12 Physical Composite Score and Mental Composite Score (MCS), were collected pre- and postoperatively. A PROM's RR was calculated as proportion of postoperative improvement to overall potential improvement.

RESULTS

In total, 740 patients were included: 359 patients with VAS back ≤7 and 381 patients with VAS back >7. The VAS back >7 cohort reported significantly greater postoperative inpatient pain (P ≤ .003, both). All preoperative and the following postoperative PROMs favored the VAS back ≤7 cohort: PROMIS-PF 2-years, VAS back overall, SF-12 Physical Composite Score 12 weeks and 1 year, SF-12 MCS 6 weeks/12 weeks, VAS leg 6 weeks, 12 weeks, 6 months, and 2 years, and ODI overall (P ≤ 0.048, all). The VAS back >7 cohort demonstrated greater delta PROMs for all VAS back and ODI except 2 years (P ≤ 0.021, all). A greater proportion of patients in the VAS back >7 group achieved minimal clinically important difference for VAS back overall, ODI 6 weeks/12 weeks, PROMIS-PF 6 weeks, and SF-12 MCS 6 weeks/6 months (P ≤ 0.044, all). The VAS back>7 cohort RR was significantly greater for VAS back 6 months and VAS leg 6 months/2 years (P ≤ 0.034, all). The VAS back ≤7 cohort's postoperative satisfaction was significantly greater for VAS back 12 weeks, VAS leg 12 weeks, and ODI 6 weeks/12 weeks (P ≤ 0.046, all).

CONCLUSIONS

Patients with greater preoperative back pain demonstrated significantly worse postoperative scores for most PROMs at most time points and significantly worse patient satisfaction for disability, back and leg pain at multiple time points.

摘要

背景

关于术前背痛严重程度对患者报告结局指标(PROMs)、恢复率(RRs)以及微创经椎间孔腰椎椎间融合术(MIS TLIF)后患者满意度的影响,相关文献有限。

方法

对MIS TLIF手术进行回顾性分析并分组:术前视觉模拟评分(VAS)背痛≤7分或VAS背痛>7分。收集术前和术后的PROMs,包括患者报告结局测量信息系统-身体功能(PROMIS-PF)、VAS背痛和腿痛评分、奥斯威斯利功能障碍指数(ODI)以及简明健康调查量表(SF-12)的生理综合评分和心理综合评分(MCS)。PROM的RR计算为术后改善程度占总体潜在改善程度的比例。

结果

共纳入740例患者:VAS背痛≤7分的患者359例,VAS背痛>7分的患者381例。VAS背痛>7分的队列术后住院疼痛明显更严重(两者P均≤0.003)。所有术前及术后的PROMs均有利于VAS背痛≤7分的队列:PROMIS-PF术后2年、总体VAS背痛、SF-12生理综合评分术后12周和1年、SF-12 MCS术后6周/12周、VAS腿痛术后6周、12周、6个月和2年,以及总体ODI(所有P≤0.048)。VAS背痛>7分的队列在除2年外的所有VAS背痛和ODI方面显示出更大的PROMs变化量(所有P≤0.021)。VAS背痛>7分组中,更多患者在总体VAS背痛、ODI术后6周/12周、PROMIS-PF术后6周以及SF-12 MCS术后6周/6个月达到最小临床重要差异(所有P≤0.044)。VAS背痛>7分队列在VAS背痛术后6个月和VAS腿痛术后6个月/2年的RR显著更高(所有P≤0.034)。VAS背痛≤7分队列在VAS背痛术后12周、VAS腿痛术后12周以及ODI术后6周/12周的术后满意度显著更高(所有P≤0.046)。

结论

术前背痛较重的患者在大多数时间点的大多数PROMs术后评分明显更差,在多个时间点的残疾、背痛和腿痛方面的患者满意度也明显更差。

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