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来自壁层胸膜的伴有雌激素和孕激素受体的胸腔内脂肪瘤。

Intrathoracic myolipoma from parietal pleura with oestrogen and progesterone receptor.

作者信息

Teh Jyh Shinn, Weng Ching-Yao, Chang Ying-Yueh, Yeh Yi-Chen, Huang Chien-Sheng

机构信息

Department of Surgery Taipei Veterans General Hospital Taipei Taiwan.

Department of Radiology Taipei Veterans General Hospital Taipei Taiwan.

出版信息

Respirol Case Rep. 2021 Sep 21;9(10):e0853. doi: 10.1002/rcr2.853. eCollection 2021 Oct.

DOI:10.1002/rcr2.853
PMID:34584729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8456152/
Abstract

Myolipoma is a rare benign lipomatous soft tissue neoplasm, occurring most frequently in adults in the abdomen, pelvis or retroperitoneum. We presented a case of a 39-year-old female with an epipleural lesion at the left paraspinal region identified using computed tomography. Magnetic resonance imaging revealed a fat-containing lesion attached to the pleura over the left paraspinal region. Surgical resection was performed, and histopathological analysis revealed a tumour composed of interlacing bundles of neoplastic smooth muscle cells with low cellularity and rare mitotic figures intermixing with mature adipocytes. The presence of oestrogen and progesterone receptors in smooth muscle cells was noted. The mass was reported as myolipoma. To the best of our knowledge, this case is the first description of an intrathoracic myolipoma.

摘要

肌脂肪瘤是一种罕见的良性脂肪瘤性软组织肿瘤,最常发生于成年人的腹部、盆腔或腹膜后。我们报告了一例39岁女性,通过计算机断层扫描发现左侧椎旁区域有一个胸膜外病变。磁共振成像显示左侧椎旁区域有一个附着于胸膜的含脂肪病变。进行了手术切除,组织病理学分析显示肿瘤由交错排列的肿瘤性平滑肌细胞束组成,细胞密度低,有丝分裂象罕见,与成熟脂肪细胞混合存在。注意到平滑肌细胞中存在雌激素和孕激素受体。该肿块被报告为肌脂肪瘤。据我们所知,该病例是胸腔内肌脂肪瘤的首例描述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b687/8456152/af1cb50d8654/RCR2-9-e0853-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b687/8456152/ecbe323fc8e7/RCR2-9-e0853-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b687/8456152/af1cb50d8654/RCR2-9-e0853-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b687/8456152/ecbe323fc8e7/RCR2-9-e0853-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b687/8456152/af1cb50d8654/RCR2-9-e0853-g003.jpg

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本文引用的文献

1
Thymoma and thymic carcinomas.胸腺瘤和胸腺癌。
Crit Rev Oncol Hematol. 2016 Mar;99:332-50. doi: 10.1016/j.critrevonc.2016.01.012. Epub 2016 Jan 19.
2
Three cases of multiple thymoma with a review of the literature.三例多发性胸腺瘤并文献复习
Jpn J Clin Oncol. 2007 Feb;37(2):146-9. doi: 10.1093/jjco/hyl147.
3
Triple thymoma with different histologic types.具有不同组织学类型的三重胸腺瘤
J Thorac Cardiovasc Surg. 2007 Mar;133(3):826-7. doi: 10.1016/j.jtcvs.2006.10.030.
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Primary thymic epithelial neoplasms showing combined features of thymoma and thymic carcinoma. A clinicopathologic study of 22 cases.呈现胸腺瘤和胸腺癌联合特征的原发性胸腺上皮性肿瘤。22例临床病理研究。
Am J Surg Pathol. 1996 Dec;20(12):1469-80. doi: 10.1097/00000478-199612000-00006.
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Recurrent thymoma: evidence for histological progression.复发性胸腺瘤:组织学进展的证据。
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