Rendón-Medina Marco Aurelio, Galeana-Pavón Alberto, Vázquez-Medina Martín Uriel, Hernández-Ordoñez Rubén, Ocharan-Hernández María Esther, Hanson-Viana Erik, Sashida-Mendez Hirosi, Mendoza-Vélez María de Los Ángeles, Pacheco-López Ricardo César
"Dr. Rubén Leñero" General Hospital, Mexico City, Mexico.
Hospital Regional Licenciado Adolfo Lopez Mateos, Mexico City, Mexico.
Plast Reconstr Surg Glob Open. 2021 Sep 22;9(9):e3819. doi: 10.1097/GOX.0000000000003819. eCollection 2021 Sep.
Free-flap monitoring is challenging to perform in some centers. It requires the availability of trained health care personnel for 24 hours a day and seven days a week. Many methods had been proposed for flap monitoring, and none of them are superior to clinical evaluation. This study aimed to present a murine model to evaluate the accuracy (sensitivity, specificity, and the positive or negative predictive values) of a device. Wistar rats weighing 240-490 g were included for intervention and data collection. A murine model of left inferior epigastric vessel flaps was implemented. Intermittent pedicle clamping was performed to calculate the accuracy of the device that detects flow obstruction. The general variables studied were age, weight, and gender. The sensitivity, specificity, and negative or predictive values were calculated. The results showed a sensitivity of 97%, a specificity of 95% with a positive predictive value of 95%, and negative predictive value of 97%. The sensitivity and specificity showed excellent results within the range of clinical security. We require more data to analyze the multiparameter monitoring to see if it is feasible and cost-effective.
在一些中心,游离皮瓣监测颇具挑战性。它需要有经过培训的医护人员能够一周七天、一天24小时随时待命。已经提出了许多皮瓣监测方法,但没有一种方法优于临床评估。本研究旨在呈现一种小鼠模型,以评估一种设备的准确性(敏感性、特异性以及阳性或阴性预测值)。纳入体重为240 - 490克的Wistar大鼠进行干预和数据收集。构建了左下腹壁血管皮瓣的小鼠模型。进行间歇性蒂部夹闭以计算检测血流阻塞的设备的准确性。所研究的一般变量包括年龄、体重和性别。计算了敏感性、特异性以及阴性或预测值。结果显示敏感性为97%,特异性为95%,阳性预测值为95%,阴性预测值为97%。在临床安全范围内,敏感性和特异性显示出优异的结果。我们需要更多数据来分析多参数监测,以确定其是否可行且具有成本效益。