Cervenka Brian, Bewley Arnaud F
Department of Otolaryngology - Head and Neck Surgery, University of California, Davis, Sacramento, California, USA.
Curr Opin Otolaryngol Head Neck Surg. 2015 Oct;23(5):393-8. doi: 10.1097/MOO.0000000000000189.
Free flap surgery has revolutionized our ability to perform composite reconstructions following ablative surgery. Although flap failure is rare (∼5%), it results in high patient morbidity if not recognized and corrected early. There are numerous means to assess flap viability. We review the recent literature on flap monitoring, and discuss the difference between techniques in regard to overall flap survival, cost, and ease of use.
The current literature on implantable Doppler, microdialysis, video-based application (Eulerian), fluorescence angiography, spectroscopy, contrast-enhanced duplex, and activated clotting time is reviewed. Of these methods, implantable Doppler and spectroscopy have the most recent and largest series of data describing efficacy with implantable Doppler, demonstrating comparable flap survival rates to clinical monitoring. Arterial implantable Doppler has the additional benefit of less false-positives than venous Doppler. Spectroscopy demonstrates promise with commensurate flap survival rates and improved salvage rates over clinical monitoring.
Clinical monitoring alone has proven to be so effective that it is difficult to demonstrate better outcomes with alternative methods. That said, a minimally invasive, reliable method that does not require physician assessment on a frequent basis would prove ideal in many small centers and academic centers limited by resident hours. Venous and, more recently, arterial monitoring have been successfully implemented at many programs. Spectroscopy appears promising, but the data are still limited.
游离皮瓣手术彻底改变了我们在切除性手术后进行复合组织重建的能力。尽管皮瓣坏死很少见(约5%),但如果不及早发现并纠正,会导致患者出现较高的发病率。有多种方法可用于评估皮瓣的存活情况。我们回顾了近期有关皮瓣监测的文献,并讨论了各种技术在皮瓣总体存活率、成本和易用性方面的差异。
对有关植入式多普勒、微透析、基于视频的应用(欧拉法)、荧光血管造影、光谱学、对比增强双功超声和活化凝血时间的当前文献进行了综述。在这些方法中,植入式多普勒和光谱学有最新且大量的数据描述其有效性,植入式多普勒显示出与临床监测相当的皮瓣存活率。与静脉多普勒相比,动脉植入式多普勒还有假阳性较少的额外优势。光谱学显示出前景,其皮瓣存活率与临床监测相当,且挽救率有所提高。
事实证明,仅靠临床监测就非常有效,以至于很难证明替代方法能带来更好的结果。话虽如此,一种微创、可靠且无需医生频繁评估的方法在许多小中心以及受住院医师工作时间限制的学术中心将被证明是理想的。静脉监测以及最近的动脉监测已在许多项目中成功实施。光谱学看起来很有前景,但数据仍然有限。