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变应性鼻炎患者呼吸困难的意外原因。

Unexpected cause of dyspnoea in a patient with allergic rhinitis.

机构信息

Imperial College London Faculty of Medicine, London, UK

Special Hospital for Pulmonary Diseases, Zagreb, Croatia.

出版信息

BMJ Case Rep. 2021 Sep 30;14(9):e244075. doi: 10.1136/bcr-2021-244075.

Abstract

A defect in one part of the immune system may affect the whole system. As a result, there may be a myriad of immunological diseases, which are often masked with the one disease that has the most prominent symptoms. This case report presents a patient with long-lasting allergic rhinitis who recently developed dyspnoea in exertion with suspected asthma development. After extensive diagnostic processing, asthma was dismissed, and diagnosis of selective IgA deficiency and coeliac disease with consequential iron deficiency anaemia was established. The patient was treated with parenteral iron and a gluten-free diet, which corrected her anaemia and led to the disappearance of dyspnoea. This paper aims to show the interplay between different immunological disorders and the possible causal connection between them.

摘要

免疫系统的一个部分出现缺陷可能会影响整个免疫系统。因此,可能会出现无数种免疫性疾病,这些疾病通常会被症状最明显的一种疾病所掩盖。本病例报告介绍了一位患有长期持续性过敏性鼻炎的患者,她最近在运动时出现呼吸困难,疑似哮喘发作。经过广泛的诊断处理,哮喘被排除,诊断为选择性 IgA 缺乏症和乳糜泻,继而导致缺铁性贫血。患者接受了肠外铁剂和无麸质饮食治疗,纠正了贫血,呼吸困难也随之消失。本文旨在展示不同免疫性疾病之间的相互作用以及它们之间可能存在的因果关系。

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