Tyler J E, Poole D F, Stack M V, Dowell T B
Arch Oral Biol. 1986;31(4):201-4. doi: 10.1016/0003-9969(86)90050-6.
Surface enamel fluoride levels were measured in deciduous canine teeth from Bristol, with non-fluoridated water supplies, and Birmingham, with fluoridated water supplies. Three populations studied were from Bristol (teeth shed before 1960), Bristol (after 1975) and Birmingham (after 1975). Up to 75 micron from the enamel surface, fluoride concentrations of post-1975 Bristol and Birmingham teeth were, respectively, X 1.3 and 3.4 greater than those of pre-1960 Bristol teeth. The increase in the Bristol teeth is presumably due mainly to the increased use of fluoride-containing toothpastes, that in Birmingham to fluoridated water plus the use of fluoride toothpastes. No difference in the rates of penetration into enamel of acid-gel induced, caries-like lesions were found between the two Bristol populations; Birmingham teeth showed a reduction of 10 per cent in penetration rate. It is suggested that raised fluoride levels in surface enamel do not reduce solubility sufficiently to account, by themselves, for the recent nationwide marked reduction in caries in children. Possibly, the raising of plaque fluoride levels is a more important factor, affecting demineralization, remineralization and bacterial activity.
对来自布里斯托尔（供水未加氟）和伯明翰（供水加氟）的乳牙犬齿的表层釉质氟含量进行了测量。所研究的三组人群分别来自布里斯托尔（1960年前脱落的牙齿）、布里斯托尔（1975年后）和伯明翰（1975年后）。在距离釉质表面75微米范围内，1975年后布里斯托尔和伯明翰牙齿的氟浓度分别比1960年前布里斯托尔牙齿的氟浓度高1.3倍和3.4倍。布里斯托尔牙齿中氟含量的增加大概主要是由于含氟牙膏使用的增加，而伯明翰牙齿中氟含量的增加则是由于加氟水以及含氟牙膏的使用。在布里斯托尔的两组人群中，酸凝胶诱导的类龋损向釉质的渗透速率没有差异；伯明翰的牙齿渗透速率降低了10%。有人提出，表层釉质中升高的氟含量本身并不能充分降低溶解度，从而无法解释近期全国范围内儿童龋齿的显著减少。可能，菌斑中氟含量的升高是一个更重要的因素，影响着脱矿、再矿化和细菌活性。
