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3,4,5-三取代异恶唑的合成及抗原生动物特性。

Synthesis and Antiprotozoal Profile of 3,4,5-Trisubstituted Isoxazoles.

机构信息

Departamento de Química, Universidade Estadual de Maringá (UEM), Maringá, Brazil.

Departamento de Ciências Básicas da Saúde, Universidade Estadual de Maringá (UEM), Maringá, Brazil.

出版信息

ChemistryOpen. 2021 Oct;10(10):930. doi: 10.1002/open.202100213.

DOI:10.1002/open.202100213
PMID:34596971
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8485824/
Abstract

Invited for this month's cover picture is the group of Prof. Fernanda Andreia Rosa at the State University of Maringá (Brazil). The cover picture shows the contribution of the SINTHET research group to the synthesis and discovery of new antiprotozoal compounds. The synthetic methodology allowed the construction of 60 new isoxazole derivatives with structural variations on the 3-, 4-, and 5-positions. The authors acknowledge Ms. Jeniffer do Nascimento Ascencio Camargo and Ms. Julia Caroline Manzano Willig for the Cover picture creation. Read the full text of their Full Paper at 10.1002/open.202100141.

摘要

本月的封面图片邀请到了来自巴西马瑞格朗州立大学的费尔南达·安德烈娅·罗莎教授的团队。该封面图片展示了 SINTHET 研究小组在合成和发现新抗原生动物化合物方面的贡献。该合成方法允许在 3-、4-和 5-位上构建 60 种具有结构变化的新型异噁唑衍生物。作者感谢 Jeniffer do Nascimento Ascencio Camargo 女士和 Julia Caroline Manzano Willig 女士创作了封面图片。阅读全文请访问 10.1002/open.202100141。

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