Rodin G M, Johnson L E, Garfinkel P E, Daneman D, Kenshole A B
Int J Psychiatry Med. 1986;16(1):49-57. doi: 10.2190/hulh-ctpr-4v17-383c.
Recent case reports have suggested an association between anorexia nervosa and/or bulimia with insulin-dependent diabetes mellitus (IDDM). Fifty-eight females aged fifteen to twenty-two with IDDM for more than one year were assessed for the presence of eating disorders. Patients were screened for eating and weight pathology using the Eating Disorder Inventory (EDI) and Eating Attitudes Test-26 (EAT-26). Glycosylated hemoglobin (HbA1) was measured to assess metabolic control. Subjects who scored above the cut-off points associated with eating and weight pathology were interviewed. Clinically significant eating and weight pathology was found in 20.7 percent of the population. Of these subjects, anorexia nervosa was found in 6.9 percent and the syndrome of bulimia, based on DSM-III criteria, was found in 6.9 percent. In patients with bulimia, there was a strong inverse correlation between bulimic symptoms and metabolic control. These findings suggest that anorexia nervosa may be more common in female adolescents with IDDM than in nondiabetic populations and that bulimic symptoms may be a risk factor for poor metabolic control.
近期的病例报告表明神经性厌食症和/或暴食症与胰岛素依赖型糖尿病（IDDM）之间存在关联。对58名年龄在15至22岁、患IDDM超过一年的女性进行了饮食失调情况评估。使用饮食失调量表（EDI）和饮食态度测试-26（EAT-26）对患者进行饮食和体重问题筛查。测量糖化血红蛋白（HbA1）以评估代谢控制情况。对得分高于与饮食和体重问题相关临界值的受试者进行了访谈。在该人群中发现有20.7%存在具有临床意义的饮食和体重问题。在这些受试者中，6.9%被诊断为神经性厌食症，根据《精神疾病诊断与统计手册》第三版（DSM-III）标准，6.9%被诊断为暴食症。在患有暴食症的患者中，暴食症状与代谢控制之间存在强烈的负相关。这些发现表明，神经性厌食症在患有IDDM的女性青少年中可能比在非糖尿病人群中更为常见，并且暴食症状可能是代谢控制不佳的一个风险因素。
