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原发性肛门直肠恶性黑色素瘤的临床表现及其处理。

Spectrum of presentation in primary anorectal malignant melanoma and its management.

机构信息

Surgical Gastroenterology and Liver Transplantation, Sir Ganga Ram Hospital, New Delhi, India.

Surgical Gastroenterology and Liver Transplantation, Sir Ganga Ram Hospital, New Delhi, India

出版信息

BMJ Case Rep. 2021 Oct 1;14(10):e245449. doi: 10.1136/bcr-2021-245449.

Abstract

The article presents a series of four patients with primary anorectal melanoma presenting to our institute between 2016 and 2021. The primary objective of the series is to give an overview of the variable presentation of this rare entity from a high-volume colorectal tertiary care centre in a developing country. The patients ranged in age from 55 to 73 years and were mostly women (except one). The clinical presentation varied from bleeding per rectum to tenesmus and mucus in stools, overlapping with those of inflammatory bowel disease and primary anorectal adenocarcinoma. All patients were treated with surgery (laparoscopic or open), ranging from local excision to abdominoperineal resection. All our patients had a good outcome after surgery with no mortality at 30 or 90 days after surgery. The article aims to present a comprehensive overview of the various options of management with evidence from the surgical literature.

摘要

本文介绍了 2016 年至 2021 年间在我院就诊的 4 例原发性肛门直肠黑色素瘤患者。本系列的主要目的是从发展中国家高容量结直肠三级护理中心的角度概述这种罕见疾病的不同表现。患者年龄在 55 岁至 73 岁之间,大多数为女性(除 1 例外)。临床表现从直肠出血到直肠坠胀和粪便中有黏液不等,与炎症性肠病和原发性肛门直肠腺癌的表现重叠。所有患者均接受手术(腹腔镜或开放性)治疗,手术范围从局部切除到腹会阴联合切除术。所有患者在手术后均取得了良好的效果,术后 30 天和 90 天内无死亡。本文旨在从手术文献中提供证据,全面概述各种治疗选择。

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[Malignant melanoma of the anorectal mucosa].[肛管直肠黏膜恶性黑色素瘤]
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本文引用的文献

1
Uncommon Anal Neoplasms.罕见的肛门肿瘤
Surg Oncol Clin N Am. 2017 Jan;26(1):143-161. doi: 10.1016/j.soc.2016.07.009.
4
Primary anorectal melanoma: an update.原发性肛门直肠黑素瘤:最新进展。
J Cancer. 2012;3:449-53. doi: 10.7150/jca.5187. Epub 2012 Oct 20.
5
Anorectal melanoma: review of 22 consecutive cases.肛管直肠黑色素瘤:22例连续病例回顾
Hepatogastroenterology. 2013 Jan-Feb;60(121):89-93. doi: 10.5754/hge12453.
6
Treatment outcomes of anorectal melanoma.肛管直肠黑色素瘤的治疗结果。
J Korean Soc Coloproctol. 2011 Feb;27(1):27-30. doi: 10.3393/jksc.2011.27.1.27. Epub 2011 Feb 28.
9
Anorectal melanoma.肛管直肠黑色素瘤
Clin Colon Rectal Surg. 2009 May;22(2):120-6. doi: 10.1055/s-0029-1223844.

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