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精神分裂症和其他精神病患者纵向研究中的流失情况;STRATA 合作的研究结果。

Attrition in longitudinal studies among patients with schizophrenia and other psychoses; findings from the STRATA collaboration.

机构信息

Institute of Clinical Sciences, Royal Victoria Hospital, Queens University Belfast, Block B, Belfast BT12 6BA, UK; Department of of Culture and Society (IKOS), Department of Social and Welfare Studies, Linköping University, Linköping, Sweden.

Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.

出版信息

Psychiatry Res. 2021 Nov;305:114211. doi: 10.1016/j.psychres.2021.114211. Epub 2021 Sep 20.

DOI:10.1016/j.psychres.2021.114211
PMID:34601449
Abstract

A major problem with longitudinal studies is the bias generated due to attrition, particularly apparent amongst patients suffering from psychotic disorders. Factors associated with study-participation were investigated as part of a larger research collaboration (STRATA). Out of 479 eligible participants, only 50 (10,4%) were successfully followed up. The present study investigated whether study participation differed depending on baseline characteristics. Results indicated that individuals who did not participate were more likely to report an alcohol use disorder while those who did respond were more likely to have been in full-time education for longer and be of white ethnicity. Participation did not differ depending on diagnosis, symptoms, GAF, age of onset or depression.

摘要

纵向研究的一个主要问题是由于损耗产生的偏差,特别是在患有精神障碍的患者中尤为明显。作为更大规模研究合作(STRATA)的一部分,研究人员调查了与研究参与相关的因素。在 479 名符合条件的参与者中,只有 50 名(10.4%)成功进行了随访。本研究调查了研究参与是否因基线特征而异。结果表明,未参与的个体更有可能报告酒精使用障碍,而那些做出回应的个体更有可能接受全日制教育时间更长,并且属于白种人。参与情况与诊断、症状、GAF、发病年龄或抑郁无关。

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