Alonso María Angeles, Díez-Álamo Antonio M, Gómez-Ariza Carlos J, Díez Emiliano, Fernandez Angel
Instituto Universitario de Neurociencia (IUNE), University of La Laguna, San Cristóbal de La Laguna, Spain.
Institute on Community Integration (INICO), University of Salamanca, Salamanca, Spain.
Front Psychol. 2021 Sep 17;12:718118. doi: 10.3389/fpsyg.2021.718118. eCollection 2021.
Non-invasive transcranial direct current stimulation (tDCS) over the left anterior temporal lobe (ATL) has been shown to cause a reduction in the rate of false memories with semantically related words. Such a reduction seems to be specific to false memories induced by the study of associative lists, but is not observed when the studied lists are categorical in nature. These findings are interpreted as evidence that the left ATL functions as an integration hub that is crucial for the binding of semantic information into coherent representations of concepts. In order to investigate whether the right ATL might also contribute to semantic integration in the processing of verbal associative material, a follow-up tDCS study was conducted with the stimulation at study lateralized on the right ATL. A sample of 75 undergraduate students participated in an experiment in which they studied 8 associative lists and 8 categorical lists. One third of the participants studied all their word lists under anodal stimulation, another third studied under cathodal stimulation and the other third under sham stimulation. Results showed that stimulation of the right ATL by tDCS does not modulate false recognition for either association-related critical words or category-related critical words. These results provide preliminary support to views positing asymmetric connectivity between the anterior temporal lobes and the semantic representational network, and provide evidence for understanding bilateral brain dynamics and the nature of semantically induced memory distortions.
对左侧颞叶前部（ATL）进行无创性经颅直流电刺激（tDCS）已被证明可降低语义相关词汇的错误记忆发生率。这种降低似乎特定于由联想列表学习诱发的错误记忆，但在学习列表本质上是分类性的情况下则未观察到。这些发现被解释为左侧ATL作为一个整合枢纽发挥作用的证据，该枢纽对于将语义信息绑定到连贯的概念表征至关重要。为了研究右侧ATL在言语联想材料处理中是否也有助于语义整合，进行了一项后续的tDCS研究，在右侧ATL进行学习时进行刺激。75名本科生参与了一项实验，他们学习了8个联想列表和8个分类列表。三分之一的参与者在阳极刺激下学习所有单词列表，另外三分之一在阴极刺激下学习，其余三分之一在假刺激下学习。结果表明，tDCS对右侧ATL的刺激并未调节与联想相关的关键单词或与类别相关的关键单词的错误识别。这些结果为假设颞叶前部与语义表征网络之间存在不对称连接的观点提供了初步支持，并为理解双侧脑动力学和语义诱发记忆扭曲的本质提供了证据。
