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Myosure成功应用于剖宫产瘢痕部位异位妊娠的治疗

Successful Use of Myosure in the Management of Cesarean Scar Ectopic Pregnancy.

作者信息

Daram Naveena R, Berry Lawrence, Fakih Mona, Alhousseini Ali

机构信息

Obstetrics and Gynecology, Oakland University William Beaumont School of Medicine, Rochester, USA.

Radiology, Wayne State University School of Medicine, Detroit, USA.

出版信息

Cureus. 2021 Aug 27;13(8):e17500. doi: 10.7759/cureus.17500. eCollection 2021 Aug.

Abstract

Cesarean scar pregnancy (CSP) is a very serious complication of a prior cesarean delivery. The major risks associated with CSP are uncontrolled hemorrhage and uterine rupture, potentially leading to future infertility. Management of CSP remains a major obstetric challenge without a well-defined therapeutic procedure. Dilation & curettage is a commonly used procedure for the treatment of CSP. However, it can be ineffective and often leads to definite infertility. Therefore, we present a case of the successful use of an alternative procedure, Myosure® hysteroscopy, in the treatment of CSP. We herein report the case of a 32-year-old G5P3013 woman who presented with vaginal bleeding and past history of three cesarean sections. She was found to have a CSP with fetal pole and cardiac activity at 6 weeks 2 days. The patient was initially treated with a systemic methotrexate injection, but there was persistence of cardiac activity. A second course of methotrexate was administered into the gestational sac, which systemically led to successful fetal cardiac arrest and downtrend of beta-human chorionic gonadotropin (HCG) level. A dilation & curettage procedure was not successful in removing products of conception. A Myosure hysteroscopy procedure, however, was successful in removing products of conception. The patient was discharged after a negative ultrasound and beta-HCG level. In our review of the literature, we found that there is no general consensus on the management of cesarean scar ectopic pregnancies. To date, there is no literature cited about the use of Myosure for cesarean scar ectopic pregnancies. However, our case suggests that Myosure can be effective for CSP and this warrants a larger-scale controlled study to better evaluate this as a treatment for this condition.

摘要

剖宫产瘢痕妊娠(CSP)是既往剖宫产术后一种非常严重的并发症。与CSP相关的主要风险是难以控制的出血和子宫破裂,可能导致未来不孕。CSP的管理仍然是一项重大的产科挑战,目前尚无明确的治疗方案。刮宫术是治疗CSP常用的方法。然而,它可能无效,且常导致绝对不孕。因此,我们报告一例成功使用替代方法——Myosure®宫腔镜治疗CSP的病例。我们在此报告一名32岁、孕5产3013的女性病例,该患者出现阴道出血,既往有三次剖宫产史。在孕6周2天时,发现她患有CSP且有胎芽和心搏。患者最初接受了甲氨蝶呤全身注射治疗,但心搏持续存在。向妊娠囊内注射了第二疗程的甲氨蝶呤,这使得胎儿心搏成功停止,β-人绒毛膜促性腺激素(HCG)水平下降。刮宫术未能成功清除妊娠物。然而,Myosure宫腔镜手术成功清除了妊娠物。超声检查及β-HCG水平呈阴性后,患者出院。在我们查阅文献时发现,对于剖宫产瘢痕部位异位妊娠的管理尚无普遍共识。迄今为止,尚无关于使用Myosure治疗剖宫产瘢痕部位异位妊娠的文献报道。然而,我们的病例表明,Myosure对CSP可能有效,这值得开展更大规模的对照研究,以更好地评估其作为这种疾病的一种治疗方法的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c39/8476203/cdfb3e3d1b1f/cureus-0013-00000017500-i01.jpg

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