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外周静脉曲张破裂导致的致命性出血。

Fatal hemorrhage from peripheral varicose vein rupture.

作者信息

Gentile Guendalina, Tambuzzi Stefano, Boracchi Michele, Del Gobbo Alessandro, Bailo Paolo, Zoia Riccardo

机构信息

Università degli Studi di Milano, Dipartimento di Scienze Biomediche per la Salute, Sezione di Medicina Legale e delle Assicurazioni, Laboratorio di Istopatologia Forense e Microbiologia Medico Legale, Milano, Italy.

Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico Milano, Anatomia Patologica, Milano, Italy.

出版信息

Autops Case Rep. 2021 Sep 23;11:e2021330. doi: 10.4322/acr.2021.330. eCollection 2021.

DOI:10.4322/acr.2021.330
PMID:34604124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8478359/
Abstract

Varix of the lower extremities is a common entity that eventually presents fatal outcome. Fatal massive bleeding due to rupture of a peripheral varicose vein is rare. The estimated incidence of these cases is 1/1000 autopsies. The case we present is unique among 26,054 autopsies performed in Milan from 1993 to 2020. It describes the investigations carried out in the suspicion of a non-natural event in an elderly woman. She was found dead at home with a large volume of blood near her feet that drained from the right leg. Pathological examination disclosed that the hemorrhage occurred by the rupture of a venous varix of the lower limb. Cases of fatal hemorrhage from peripheral variceal rupture are insidious and require proper characterization. The bloodstain pattern analysis, careful autopsy dissection by layers to demonstrate the rupture, and histologic examination of the lesion are the essential elements to find out the actual cause of death.

摘要

下肢静脉曲张是一种常见病症,最终可能导致致命后果。因外周静脉曲张破裂导致的致命性大出血较为罕见。此类病例的估计发病率为千分之一尸检。我们呈现的这个病例在1993年至2020年于米兰进行的26,054例尸检中是独一无二的。它描述了对一名老年女性疑似非自然事件展开的调查。她被发现死于家中,右脚附近有大量从右腿流出的血液。病理检查显示出血是由下肢静脉静脉曲张破裂所致。外周静脉曲张破裂导致致命出血的病例较为隐匿,需要进行恰当的特征描述。血迹模式分析、逐层仔细的尸检解剖以证明破裂情况以及对病变进行组织学检查是查明实际死因的关键要素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b79a/8478359/477e82b37858/autopsy-11-e2021330-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b79a/8478359/68e4370a7ce5/autopsy-11-e2021330-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b79a/8478359/477e82b37858/autopsy-11-e2021330-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b79a/8478359/68e4370a7ce5/autopsy-11-e2021330-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b79a/8478359/477e82b37858/autopsy-11-e2021330-g02.jpg

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A forensic analysis on 53 cases of complex suicides and one complicated assessed at the Bureau of Legal Medicine of Milan (Italy).对米兰(意大利)法医鉴定局 53 例复杂自杀和 1 例复杂评估案例的法医分析。
Forensic Sci Int. 2021 Feb;319:110662. doi: 10.1016/j.forsciint.2020.110662. Epub 2020 Dec 25.
2
Fatal bleeding caused by a ruptured varicose vein.静脉曲张破裂导致的致命出血。
Med Leg J. 2020 Mar;88(1):41-44. doi: 10.1177/0968533219885621. Epub 2020 Jan 13.
3
Haemorrhage from varicose veins and varicose ulceration: A systematic review.
静脉曲张和静脉曲张溃疡出血:系统评价。
Int Wound J. 2018 Oct;15(5):829-833. doi: 10.1111/iwj.12934. Epub 2018 May 28.
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Ruptured varicose veins and fatal hemorrhage.静脉曲张破裂与致命性出血。
Forensic Sci Med Pathol. 2018 Jun;14(2):244-247. doi: 10.1007/s12024-017-9897-y. Epub 2017 Jul 11.
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Sudden death by rupture of a varicose vein: Case report and review of literature.静脉曲张破裂导致的猝死:病例报告及文献综述
Med Leg J. 2017 Mar;85(1):47-50. doi: 10.1177/0025817216678712. Epub 2016 Nov 15.
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[Unattended fatal haemorrhage associated with spontaneous rupture of peripheral varicosity].[与外周静脉曲张自发性破裂相关的无人照料的致命性出血]
Soud Lek. 2012 Apr;57(2):18-20.
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[Fatal exsanguination due to ruptured vericose vein of the lower leg: case report].
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