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注射部位附近锝-亚甲基二膦酸盐过量存在的检测——病例报告

Detection of Excess Presence of Tc-MDP Near Injection Site-A Case Report.

作者信息

Crowley James R, Barvi Iryna, Greulich Debbie, Kiser Jackson W

机构信息

Department of Molecular Imaging, Carilion Clinic, Roanoke, VA, United States.

Lucerno Dynamics LLC, Cary, NC, United States.

出版信息

Front Med (Lausanne). 2021 Sep 17;8:728542. doi: 10.3389/fmed.2021.728542. eCollection 2021.

DOI:10.3389/fmed.2021.728542
PMID:34604265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8484323/
Abstract

Nuclear medicine extravasations and prolonged venous stasis may cause poor quality and quantification errors that can affect image interpretation and patient management. Radiopharmaceutical remaining near the administration site means that some portion of the radioactivity is not circulating as required for the prescribed uptake period. This case describes how detection of excess presence of Tc-MDP near the injection site enabled the technologist to apply mitigation tactics early in the uptake process. It also suggests that detecting an extravasation or stasis early in the injection process can be important for image interpretation and minimizing radiation dose to tissue.

摘要

核医学外渗和长时间静脉淤滞可能会导致图像质量不佳和定量误差,进而影响图像解读和患者管理。放射性药物残留在给药部位附近意味着部分放射性在规定的摄取期内未按要求循环。本病例描述了如何通过检测注射部位附近过量存在的锝-亚甲基二膦酸盐(Tc-MDP),使技术人员能够在摄取过程早期采取缓解措施。这也表明,在注射过程早期检测到外渗或淤滞对于图像解读和将组织辐射剂量降至最低可能很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12e2/8484323/06de117ed938/fmed-08-728542-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12e2/8484323/39e5ce4acc04/fmed-08-728542-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12e2/8484323/4a1e84a06f1c/fmed-08-728542-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12e2/8484323/06de117ed938/fmed-08-728542-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12e2/8484323/39e5ce4acc04/fmed-08-728542-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12e2/8484323/4a1e84a06f1c/fmed-08-728542-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12e2/8484323/06de117ed938/fmed-08-728542-g0003.jpg

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本文引用的文献

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Front Med (Lausanne). 2021 Jun 28;8:684157. doi: 10.3389/fmed.2021.684157. eCollection 2021.
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Patient-specific Extravasation Dosimetry Using Uptake Probe Measurements.采用摄取探头测量的患者特异性外渗剂量学。
Health Phys. 2021 Mar 1;120(3):339-343. doi: 10.1097/HP.0000000000001375.
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Radioisotope Imaging and Therapy for Bone Metastasis in Men With Castration-Resistant Prostate Cancer.
去势抵抗性前列腺癌男性骨转移的放射性核素成像与治疗
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Impact of an 18F-FDG PET/CT Radiotracer Injection Infiltration on Patient Management-A Case Report.18F-FDG PET/CT放射性示踪剂注射渗漏对患者管理的影响——病例报告
Front Med (Lausanne). 2018 May 15;5:143. doi: 10.3389/fmed.2018.00143. eCollection 2018.
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