Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia.
J Nucl Med. 2014 Apr;55(4):608-15. doi: 10.2967/jnumed.113.133447. Epub 2014 Feb 18.
Radionuclide renal scintigraphy provides important functional data to assist in the diagnosis and management of patients with a variety of suspected genitourinary tract problems, but the procedures are underutilized. Maximizing the utility of the available studies (as well as the perception of utility by referring physicians) requires a clear understanding of the clinical question, attention to quality control, acquisition of the essential elements necessary to produce an informed interpretation, and production of a report that presents a coherent impression that specifically addresses the clinical question and is supported by data contained in the report. To help achieve these goals, part 1 of this review covers information that should be provided to the patient before the scan, describes the advantages and limitations of the available radiopharmaceuticals, discusses quality control elements needed to optimize the study, summarizes approaches to the measurements of renal function, and focuses on recommended quantitative indices and their diagnostic applications. Although the primary focus is the adult patient, aspects of the review also apply to the pediatric population.
放射性核素肾闪烁显像为诊断和处理各种疑似泌尿生殖系统疾病提供了重要的功能数据，但该检查的应用并不充分。为了最大限度地利用现有的研究（以及让转诊医生感受到其有用性），需要清楚地了解临床问题，注重质量控制，获取产生知情解读所必需的基本要素，并生成一份报告，该报告提供一个连贯的印象，明确针对临床问题，并由报告中包含的数据支持。为了帮助实现这些目标，本综述的第 1 部分涵盖了在扫描前应向患者提供的信息，描述了现有放射性药物的优缺点，讨论了优化研究所需的质量控制要素，总结了肾功能测量方法，并重点介绍了推荐的定量指标及其诊断应用。尽管主要重点是成年患者，但该综述的某些方面也适用于儿科人群。
