SAMRC Microbial Water Quality Monitoring Centre, University of Fort Hare, Alice 5700, South Africa; Department of Pure and Applied Chemistry, University of Fort Hare, Alice 5700, South Africa.
SAMRC Microbial Water Quality Monitoring Centre, University of Fort Hare, Alice 5700, South Africa; Department of Pure and Applied Chemistry, University of Fort Hare, Alice 5700, South Africa; Department of Chemistry and Chemical Technology, National University of Lesotho, P. O. Roma, 180, Lesotho.
Mar Pollut Bull. 2021 Dec;173(Pt A):113012. doi: 10.1016/j.marpolbul.2021.113012. Epub 2021 Oct 1.
The presence of pharmaceuticals in surface water and sediment has sparked up a global concern, as they could cause harm to human health. In this study, we investigated five pharmaceuticals (caffeine, carbamazepine, sulfamethoxazole, testosterone, and trimethoprim) in surface water and sediment samples from Swartkops River Estuary and Markman Stormwater Canal, in the Eastern Cape Province, South Africa. Ultra-Performance Liquid Chromatography (UPLC) systems coupled with a hyphenated quadrupole-time-of-flight mass spectrometry (QTOF-MS) was used for the analysis. Of the five pharmaceuticals investigated, three were detected in sediment samples at concentrations ranging from BDL - 23.86 μg/kg (dw). Caffeine and sulfamethoxazole were below the detection limit. The finding of this current study suggests that Markman and Motherwell's stormwater canals were potential contributors to pollution in Swartkops River Estuary. Ecotoxicity risk assessment indicated that trimethoprim and carbamazepine could constitute potential risk to aquatic organisms in Markman Canal and Swartkops Estuary, suggesting the need for proper control measure to prevent the pollution from toxicants in aquatic resources.
五种药品（咖啡因、卡马西平、磺胺甲恶唑、睾丸激素和甲氧苄啶）在南非东开普省斯瓦特克普斯河口和马克曼雨水渠的地表水和沉积物样本中进行了研究。采用超高效液相色谱（UPLC）系统与串联四极杆飞行时间质谱（QTOF-MS）联用的方法进行分析。在所研究的五种药品中，有三种在沉积物样本中被检测到，浓度范围为 BDL-23.86μg/kg（干重）。咖啡因和磺胺甲恶唑低于检测限。本研究的结果表明，马克曼和马瑟韦尔的雨水渠可能是斯瓦特克普斯河口污染的潜在来源。生态毒性风险评估表明，甲氧苄啶和卡马西平可能对马克曼运河和斯瓦特克普斯河口的水生生物构成潜在风险，这表明需要采取适当的控制措施来防止水生资源中毒物的污染。
